The use of human iPSC‐derived alveolar organoids to explore SARS‐CoV‐2 variant infections and host responses
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Medical Virology"
DOI: 10.1002/jmv.29579
Abstract: Severe acute respiratory syndrome‐related coronavirus 2 (SARS‐CoV‐2) primarily targets the respiratory system. Physiologically relevant human lung models are indispensable to investigate virus‐induced host response and disease pathogenesis. In this study, we generated human induced pluripotent… read more here.
Keywords: sars cov; host; derived alveolar; ipsc derived ... See more keywords
Human Pluripotent Stem Cell-Derived Alveolar Organoids for Gene-editing and Lung Adenocarcinomas Modeling
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.118304
Abstract: Human pluripotent stem cell (hPSC)-derived alveolar organoids have emerged as valuable tools for studying lung development, modeling pulmonary diseases, and drug discovery, though their application has been hindered by laborious differentiation protocols and technical complexity.… read more here.
Keywords: lung; stem cell; pluripotent stem; human pluripotent ... See more keywords