Design and synthesis of N–acetylglucosamine derived 5a-carbasugar analogues as glycosidase inhibitors
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DOI: 10.1016/j.tet.2018.02.063
Abstract: Abstract An efficient synthesis of new six-membered carbasugars in both L-form and D-form starting from N–acetylglucosamine is described. The key synthetic steps involved regioselective protection and deprotection, Ferrier carbocyclization, Peterson olefination, hydroboration and stereoselective epoxidation… read more here.
Keywords: design synthesis; synthesis acetylglucosamine; synthesis; derived carbasugar ... See more keywords