Sheep-derived cell immortalization through the expression of cell cycle regulators and biological characterization using transcriptomes.
Sign Up to like & getrecommendations! Published in 2023 at "Cell biology international"
DOI: 10.1002/cbin.12034
Abstract: Sheep are important domestic animals for the production of wool and meat. Although numerous cultured cell lines from humans and mice have been established, the number of cell lines derived from sheep is limited. To… read more here.
Keywords: cell; biological characterization; derived cell; sheep derived ... See more keywords
Biodistribution of unmodified cardiosphere-derived cell extracellular vesicles using single RNA tracing.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of extracellular vesicles"
DOI: 10.1002/jev2.12178
Abstract: Extracellular vesicles (EVs) are potent signalling mediators. Although interest in EV translation is ever-increasing, development efforts are hampered by the inability to reliably assess the uptake of EVs and their RNA cargo. Here, we establish… read more here.
Keywords: extracellular vesicles; derived cell; cardiosphere derived; biodistribution unmodified ... See more keywords
Analysis of Donor-Derived Cell-Free DNA with 3-Year Outcomes in Heart Transplant Recipients
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Heart and Lung Transplantation"
DOI: 10.1016/j.healun.2017.01.172
Abstract: Purpose: Elevated donor-derived cell-free DNA (dd-cfDNA) has been observed in transplant patients undergoing acute rejection, but the relationship between dd-cfDNA and long term outcomes has not previously been studied. In this exploratory study, serially measured… read more here.
Keywords: heart; free dna; cell free; heart transplant ... See more keywords
Early Phase Circulating Donor-Derived Cell-Free DNA in Patients after Lung Transplantation
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Heart and Lung Transplantation"
DOI: 10.1016/j.healun.2021.01.459
Abstract: Purpose Detection of donor-derived cell-free DNA (dd-cfDNA) in circulating blood of posttransplant recipients is a clinically informative tool to predict acute allograft injury and rejection, although its reliability and feasibility have not been extensively studied… read more here.
Keywords: cfdna; donor derived; derived cell; phase ... See more keywords
Use of Donor-Derived Cell-Free DNA for Assessment of Allograft Injury in Kidney Transplant Recipients During the Time of the Coronavirus Disease 2019 Pandemic.
Sign Up to like & getrecommendations! Published in 2020 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2020.07.013
Abstract: BACKGROUND Kidney allograft biopsy is the gold standard for diagnosis of rejection. Under the current extraordinary circumstances of the coronavirus disease 2019 (COVID-19), in which social distancing is key to limiting the spread of the… read more here.
Keywords: disease 2019; cell free; donor derived; derived cell ... See more keywords
Umbilical Cord Blood and Cord Tissue-Derived Cell Therapies for Neonatal Morbidities: Current Status and Future Challenges
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells Translational Medicine"
DOI: 10.1093/stcltm/szab024
Abstract: Abstract Cell therapies are an emerging focus for neonatal research, with benefits documented for neonatal respiratory, neurological, and cardiac conditions in pre-clinical studies. Umbilical cord blood (UCB) and umbilical cord (UC) tissue-derived cell therapy is… read more here.
Keywords: cord; cell; cord tissue; derived cell ... See more keywords
Donor-Derived Cell-free DNA for Personalized Immunosuppression in Renal Transplantation
Sign Up to like & getrecommendations! Published in 2022 at "Therapeutic Drug Monitoring"
DOI: 10.1097/ftd.0000000000001023
Abstract: Background: The long-term outcomes of solid organ transplantation remain suboptimal. Therefore, appropriate biomarkers are needed in addition to immunosuppressive drugs and other traditional approaches for graft monitoring to achieve personalized immunosuppression and reduce premature graft… read more here.
Keywords: personalized immunosuppression; derived cell; cell free; cfdna ... See more keywords
Donor-derived Cell-free DNA Identifies Antibody-mediated Rejection in Donor Specific Antibody Positive Kidney Transplant Recipients
Sign Up to like & getrecommendations! Published in 2018 at "Transplantation Direct"
DOI: 10.1097/txd.0000000000000821
Abstract: Background Elevated levels of donor-derived cell-free DNA (dd-cfDNA) in the plasma of renal allograft recipients indicates organ injury and an increased probability of active rejection. Donor-specific antibodies (DSA) to HLA antigens are associated with risk… read more here.
Keywords: dsa; cell free; donor derived; derived cell ... See more keywords
Causes of Renal Allograft Injury in Recipients With Normal Donor-derived Cell-free DNA
Sign Up to like & getrecommendations! Published in 2021 at "Transplantation Direct"
DOI: 10.1097/txd.0000000000001135
Abstract: Background. Donor-derived cell-free DNA (dd-cfDNA) is a noninvasive biomarker for the early detection of organ transplant rejection and other causes of graft injury. For nonrejection renal injuries, there is little information about the performance characteristics… read more here.
Keywords: cell free; donor derived; derived cell; free dna ... See more keywords
Absolute quantification of donor‐derived cell‐free DNA as a marker of rejection and graft injury in kidney transplantation: Results from a prospective observational study
Sign Up to like & getrecommendations! Published in 2019 at "American Journal of Transplantation"
DOI: 10.1111/ajt.15416
Abstract: Donor‐derived cell‐free DNA (dd‐cfDNA) is a noninvasive biomarker for comprehensive monitoring of allograft injury and rejection in kidney transplantation (KTx). dd‐cfDNA quantification of copies/mL plasma (dd‐cfDNA[cp/mL]) was compared to dd‐cfDNA fraction (dd‐cfDNA[%]) at prespecified visits… read more here.
Keywords: rejection; cell free; cfdna; transplantation ... See more keywords
Donor‐derived cell‐free DNA levels predict graft injury in liver transplant recipients
Sign Up to like & getrecommendations! Published in 2021 at "American Journal of Transplantation"
DOI: 10.1111/ajt.16835
Abstract: Donor‐derived cell‐free DNA (dd‐cfDNA) has been evaluated as a rejection marker in organ transplantation. This study sought to assess the utility of dd‐cfDNA to diagnose graft injury in liver transplant recipients (LTR) and as a… read more here.
Keywords: derived cell; graft injury; cfdna; rejection ... See more keywords