Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids
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DOI: 10.1007/s00401-021-02361-9
Abstract: APOE4 is a strong genetic risk factor for Alzheimer’s disease and Dementia with Lewy bodies; however, how its expression impacts pathogenic pathways in a human-relevant system is not clear. Here using human iPSC-derived cerebral organoid… read more here.
Keywords: pathology; cerebral organoids; derived cerebral; ipsc derived ... See more keywords