Design, Synthesis, and Biological Evaluation of Aromatic Amide-Substituted Benzimidazole-Derived Chalcones. The Effect of Upregulating TP53 Protein Expression
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DOI: 10.3390/molecules25051162
Abstract: A series of benzimidazole-derived chalcones containing aromatic amide substituent were designed and synthesized. All of the chalcone compounds were tested for their in vitro antitumor activity against human cancer cell lines (HCT116, HepG2, A549, and… read more here.
Keywords: aromatic amide; benzimidazole derived; tp53 protein; derived chalcones ... See more keywords