Characterization of phenotypic and genotypic diversity in subclones derived from a clonal cell line
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DOI: 10.1002/btpr.2666
Abstract: Regulatory guidelines require the sponsors to provide assurance of clonality of the production cell line, and when such evidence is not available, additional studies are typically required to further ensure consistent long‐term manufacturing of the… read more here.
Keywords: cell line; derived clonal; diversity; phenotypic genotypic ... See more keywords