Colorectal adenocarcinoma‐derived EGFR mutants are oncogenic and sensitive to EGFR‐targeted monoclonal antibodies, cetuximab and panitumumab
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DOI: 10.1002/ijc.32499
Abstract: Somatic mutations of epidermal growth factor receptor (EGFR) occur in ~3% of colorectal cancer (CRC) patients. Here, through systematic functional screening of 21 recurrent EGFR mutations selected from public data sets, we show that 11… read more here.
Keywords: derived egfr; egfr; egfr mutants; adenocarcinoma derived ... See more keywords