microRNA-21-5p from M2 macrophage-derived extracellular vesicles promotes the differentiation and activity of pancreatic cancer stem cells by mediating KLF3.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biology and toxicology"
DOI: 10.1007/s10565-021-09597-x
Abstract: AIM Given the fact that tumor-associated macrophage-derived extracellular vesicles (EVs) are attributable to tumor aggressiveness, this research intends to decode the mechanism of M2 macrophage-derived EVs in the differentiation and activities of pancreatic cancer (PaCa)… read more here.
Keywords: differentiation; derived evs; macrophage derived; stem ... See more keywords
Regulatory T cell-derived extracellular vesicles modify dendritic cell function
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-24531-8
Abstract: Regulatory T cells (Treg) are a subpopulation of T cells that maintain tolerance to self and limit other immune responses. They achieve this through different mechanisms including the release of extracellular vesicles (EVs) such as… read more here.
Keywords: extracellular vesicles; treg derived; regulatory cell; derived evs ... See more keywords
New Optical Imaging Reporter-labeled Anaplastic Thyroid Cancer-Derived Extracellular Vesicles as a Platform for In Vivo Tumor Targeting in a Mouse Model
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-31998-y
Abstract: Extracellular vesicles (EVs), originating from multivesicular bodies by invagination of the endosomal membrane, are communication channels between distant cells. They are natural carriers of exogeneous cellular materials and have been exploited as drug delivery carriers… read more here.
Keywords: cell derived; optical imaging; cancer; derived evs ... See more keywords
Isoforms of soluble vascular endothelial growth factor in stress-related mental disorders: a cross-sectional study
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-96313-8
Abstract: Vascular endothelial growth factor (VEGF) has been implicated in the pathophysiology of stress-related mental disorders. However, VEGF levels have seldom been compared across mental disorders and never by isoforms. Pathophysiological processes involving leakage of astrocyte-derived… read more here.
Keywords: vegf; stress related; mental disorders; astrocyte derived ... See more keywords
Controlling the fate of regenerative cells with engineered platelet-derived extracellular vesicles.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d1nr08108j
Abstract: Extracellular vesicles (EVs) have emerged as cell-free nanotherapeutic agents for the potential treatment of multiple diseases and for tissue engineering and regenerative medicine strategies. Nevertheless, the field has typically relied on EVs derived from stem… read more here.
Keywords: extracellular vesicles; platelet; controlling fate; platelet derived ... See more keywords
Pseudomonas aeruginosa-Derived Extracellular Vesicles Modulate Corneal Inflammation: Role in Microbial Keratitis?
Sign Up to like & getrecommendations! Published in 2023 at "Infection and Immunity"
DOI: 10.1128/iai.00036-23
Abstract: Pseudomonas aeruginosa keratitis occurs following trauma, in immunocompromised patients, and in otherwise healthy contact lens wearers. Characterized by a light-blocking infiltrate, P. aeruginosa keratitis is the most serious complication associated with contact lens wear and,… read more here.
Keywords: pseudomonas aeruginosa; keratitis; aeruginosa derived; aeruginosa keratitis ... See more keywords
MSC-Derived Extracellular Vesicles Activate Mitophagy to Alleviate Renal Ischemia/Reperfusion Injury via the miR-223-3p/NLRP3 Axis
Sign Up to like & getrecommendations! Published in 2022 at "Stem Cells International"
DOI: 10.1155/2022/6852661
Abstract: Background MSC-derived extracellular vehicles (EVs) exhibit a protective functional role in renal ischemia/reperfusion injury (RIRI). Recent studies have revealed that mitophagy could be a potential target process in the treatment of RIRI. However, whether MSC-derived… read more here.
Keywords: derived evs; mir 223; riri; msc derived ... See more keywords
Abstract 2174: Evaluation of extracellular vesicles (EVs) as potential predictors of response to immunotherapy (IO) in triple negative early and advanced breast cancer (BC): preliminary evidence from the IRIS project
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2174
Abstract: BackgroundEvaluation of extracellular vescicles (EVs) has been identified as a potential predictive biomarker in patients treated with IO. In particular, Glypican-1 (GPC-1), was reported to be abnormally expressed in BC tissues and GPC-1+ EVs resulted… read more here.
Keywords: iris project; cancer; early advanced; triple negative ... See more keywords
Myeloid Extracellular Vesicles: New Players in Indirect Lung Injury
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2022-0380ed
Abstract: Infection, either direct (pulmonary) or indirect (extrapulmonary), is the most common precipitating factor for the development of acute respiratory distress syndrome (ARDS). Since the coronavirus disease (COVID-19) pandemic, we have started to develop pharmacotherapies specifically… read more here.
Keywords: cell; effect; lung injury; injury ... See more keywords
Effects of Cyclooxygenase-2 in Canine Melanoma-derived Extracellular Vesicles on Tumor Microenvironment In Vitro
Sign Up to like & getrecommendations! Published in 2022 at "AntiCancer Research"
DOI: 10.21873/anticanres.16044
Abstract: Abstract Background/Aim: Tumor cell-derived extracellular vesicles (TEVs) promote tumor growth and metastasis; thus, they have drawn the attention of researchers. TEVs regulate the tumor microenvironment by facilitating crosstalk between immune and stromal cells. Macrophages are… read more here.
Keywords: canine melanoma; melanoma; derived extracellular; melanoma derived ... See more keywords
Tumor-Derived Extracellular Vesicles Regulate Cancer Progression in the Tumor Microenvironment
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2021.796385
Abstract: Extracellular vesicles (EVs) are nanosized particles released by numerous kinds of cells, which are now increasingly considered as essential vehicles of cell-to-cell communication and biomarkers in disease diagnosis and treatment. They contain a variety of… read more here.
Keywords: extracellular vesicles; derived evs; tumor microenvironment; tumor derived ... See more keywords