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   Articles with "derived exosomal" as a keyword



Adipocyte‐Derived Exosomal MTTP Suppresses Ferroptosis and Promotes Chemoresistance in Colorectal Cancer

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recommendations! Published in 2022 at "Advanced Science"

DOI: 10.1002/advs.202203357

Abstract: Obesity is closely related to a poor prognosis in patients with advanced colorectal cancer (CRC), but the mechanisms remain unclear. Ferroptosis is a form of nonapoptotic cell death characterized by lipid reactive oxygen species (ROS)… read more here.

Keywords: mttp; derived exosomal; adipocyte derived; colorectal cancer ... See more keywords

Chondrocytes-derived exosomal miR-8485 regulated the Wnt/β-catenin pathways to promote chondrogenic differentiation of BMSCs.

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recommendations! Published in 2019 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2019.12.065

Abstract: In indirect co-culture system, chondrocytes can induce differentiation of bone marrow mesenchymal stem cells (BMSCs) to chondrocytes without additional inducer. The participation of microRNAs (miRNAs) may take part in the chondrogenic differentiation. Present study aimed… read more here.

Keywords: derived exosomal; mir 8485; differentiation; chondrogenic differentiation ... See more keywords

Brown adipocyte-derived exosomal miR-132-3p suppress hepatic Srebf1 expression and thereby attenuate expression of lipogenic genes.

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recommendations! Published in 2020 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2020.05.090

Abstract: Recent evidence has revealed a novel signaling mechanism through which brown adipose tissue (BAT)-derived exosomal microRNAs (miRNAs) influence hepatic gene expression. Here, we uncover neuronal control of these miRNAs and identify exosomal miR-132-3p as a… read more here.

Keywords: mir 132; srebf1; derived exosomal; expression ... See more keywords

BMSCs-derived exosomal microRNA-150-5p attenuates myocardial infarction in mice.

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recommendations! Published in 2021 at "International immunopharmacology"

DOI: 10.1016/j.intimp.2021.107389

Abstract: OBJECTIVE MicroRNAs (miRNAs) have engaged in the progression of myocardial infarction (MI). Nevertheless, the mechanism of miR-150-5p in MI is still in its infancy. Therefore, the present study was set out to investigate the effect… read more here.

Keywords: derived exosomal; mir 150; expression; mice ... See more keywords

Plasma-derived exosomal tRF-3004a as a diagnostic biomarker for colorectal cancer.

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recommendations! Published in 2025 at "Scientific reports"

DOI: 10.1038/s41598-025-30113-2

Abstract: Transfer RNA-derived small RNAs (tsRNAs) play crucial regulatory roles in tumour biology; however, their potential as biomarkers for colorectal cancer (CRC) remains underexplored. Plasma samples from 123 patients with CRC and 79 healthy controls (HCs)… read more here.

Keywords: plasma derived; exosomal trf; derived exosomal; trf 3004a ... See more keywords

RETRACTED ARTICLE: Tumor-derived exosomal microRNA-15b-5p augments laryngeal cancer by targeting TXNIP

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recommendations! Published in 2022 at "Cell Cycle"

DOI: 10.1080/15384101.2021.2022845

Abstract: Statement of Retraction We, the Editors and Publisher of the journal Cell Cycle, have retracted the following article: Feng Yu, Ying Lin, Guojie Tan, Maomao Ai, Huicheng Gong, Wei Liu, Jiali Huang and Zirou Zou.… read more here.

Keywords: article; derived exosomal; microrna 15b; tumor derived ... See more keywords

Small RNA sequencing reveals placenta-derived exosomal microRNAs associated with preeclampsia

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recommendations! Published in 2022 at "Journal of Hypertension"

DOI: 10.1097/hjh.0000000000003112

Abstract: Objective: Preeclampsia is one of the most important complications during pregnancy and the leading cause of maternal morbidity and mortality; however, the pathogenesis of preeclampsia remains partially misunderstood. The aim of this study was to… read more here.

Keywords: derived exosomal; rna sequencing; differentially expressed; preeclampsia ... See more keywords

UCMSCs‐derived exosomal circHIPK3 promotes ulcer wound angiogenesis of diabetes mellitus via miR‐20b‐5p/Nrf2/VEGFA axis

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recommendations! Published in 2022 at "Diabetic Medicine"

DOI: 10.1111/dme.14968

Abstract: Experiments confirmed that circular RNAs contributed to the pathogenesis of diabetic foot ulcers (DFUs). CircHIPK3 was upregulated in type 2 diabetes mellitus (T2DM), but its role in DFU remained unknown. Our study aimed to investigate… read more here.

Keywords: exosomal circhipk3; derived exosomal; diabetes mellitus; ucmscs derived ... See more keywords

Cancer‐associated fibroblast‐derived exosomal microRNA‐24‐3p enhances colon cancer cell resistance to MTX by down‐regulating CDX2/HEPH axis

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recommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.15765

Abstract: MicroRNA‐24‐3p (miR‐24‐3p) has been implicated as a key promoter of chemotherapy resistance in numerous cancers. Meanwhile, cancer‐associated fibroblasts (CAFs) can secret exosomes to transfer miRNAs, which mediate tumour development. However, little is known regarding the… read more here.

Keywords: mir; heph; derived exosomal; resistance ... See more keywords

Profiling of plasma-derived exosomal RNA expression in patients with periodontitis: a pilot study.

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recommendations! Published in 2022 at "Oral diseases"

DOI: 10.1111/odi.14145

Abstract: OBJECTIVE This study aimed to profile differentially expressed (DE) exosomal RNAs in healthy subjects and periodontitis patients and compare their levels before and after treatment. MATERIALS AND METHODS Plasma samples from healthy subjects and patients… read more here.

Keywords: derived exosomal; plasma derived; mir; treatment ... See more keywords

MiR-181a-5p Delivered by Adipose-Derived Mesenchymal Stem Cell Exosomes Alleviates Klebsiella pneumonia Infection-Induced Lung Injury by Targeting STAT3 Signaling

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recommendations! Published in 2022 at "Mediators of Inflammation"

DOI: 10.1155/2022/5188895

Abstract: Background Klebsiella pneumoniae (K. pneu) is a leading cause of gram-negative pneumonia, which requires effective treatment. Adipose-derived mesenchymal stem cell- (ADSC-) derived exosomal microRNAs (miRNAs) have presented the inhibitory effect of multiple diseases. However, the… read more here.

Keywords: infection induced; derived exosomal; mir 181a; infection ... See more keywords