Application of plant-derived exosome-like nanoparticles in drug delivery
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2023.2202242
Abstract: Abstract Exosomes are one type of extracellular vesicles with size ranging from 30 to 150 nm, which are involved in intercellular communication by transporting specific proteins, nucleic acids, and low molecular weight metabolites. The size and… read more here.
Keywords: derived exosome; exosome like; drug delivery; plant derived ... See more keywords
Enhancing Functional Recovery after Segmental Nerve Defect using Nerve Allograft treated with Plasma-Derived Exosome.
Sign Up to like & getrecommendations! Published in 2023 at "Plastic and reconstructive surgery"
DOI: 10.1097/prs.0000000000010389
Abstract: BACKGROUND Nerve injuries can result in detrimental functional outcomes. Currently, autologous nerve graft offers the best outcome for segmental peripheral nerve injury. Allografts are alternatives, but do not have comparable results. This study evaluated if… read more here.
Keywords: derived exosome; nerve; functional recovery; plasma derived ... See more keywords
Abstract 2349: Investigating the effect of ECM stiffness on macrophage-derived exosome secretion and PDAC organoid progression
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2349
Abstract: Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate of only 11%. Current treatments that mostly target the cancer cells themselves, have not been able to significantly improve survival rates, meaning there is an urgent… read more here.
Keywords: ecm stiffness; derived exosome; exosome secretion; macrophage derived ... See more keywords
The role of mesenchymal stem cell-derived exosome in epigenetic modifications in inflammatory diseases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1166536
Abstract: Epigenetic modification is a complex process of reversible and heritable alterations in gene function, and the combination of epigenetic and metabolic alterations is recognized as an important causative factor in diseases such as inflammatory bowel… read more here.
Keywords: derived exosome; stem cell; mesenchymal stem; epigenetic modifications ... See more keywords
Strawberry-Derived Exosome-Like Nanoparticles Prevent Oxidative Stress in Human Mesenchymal Stromal Cells
Sign Up to like & getrecommendations! Published in 2021 at "Biomolecules"
DOI: 10.3390/biom11010087
Abstract: Plant-derived exosome-like nanovesicles (EPDENs) have recently been isolated and evaluated as potential bioactive nutraceutical biomolecules. It has been hypothesized that EPDENs may exert their activity on mammalian cells through their specific cargo. In this study,… read more here.
Keywords: human mesenchymal; mesenchymal stromal; exosome like; derived exosome ... See more keywords
Plant-Derived Exosome-like Nanoparticles for Biomedical Applications and Regenerative Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041053
Abstract: Plant-derived exosome-like nanoparticles (PDENs) comprise various bioactive biomolecules. As an alternative cell-free therapeutic approach, they have the potential to deliver nano-bioactive compounds to the human body, and thus lead to various anti-inflammatory, antioxidant, and anti-tumor… read more here.
Keywords: derived exosome; regenerative therapy; exosome like; plant derived ... See more keywords
Feasibility of Leukemia-Derived Exosome Enrichment and Co-isolated dsDNA Sequencing in Acute Myeloid Leukemia Patients: A Proof of Concept for New Leukemia Biomarkers Detection
Sign Up to like & getrecommendations! Published in 2022 at "Cancers"
DOI: 10.3390/cancers14184504
Abstract: Simple Summary The present pilot study aimed at investigating the feasibility of a leukemia-derived exosome enrichment approach followed by exosomal dsDNA target re-sequencing for adult Acute Myeloid Leukemias (AML) marker detection. To our knowledge, this… read more here.
Keywords: derived exosome; leukemia derived; leukemia; exosome enrichment ... See more keywords
Dietary-Derived Exosome-like Nanoparticles as Bacterial Modulators: Beyond MicroRNAs
Sign Up to like & getrecommendations! Published in 2023 at "Nutrients"
DOI: 10.3390/nu15051265
Abstract: There is increasing evidence that food is an important factor that influences the composition of the gut microbiota. Usually, all the attention has been focused on nutrients such as lipids, proteins, vitamins, or polyphenols. However,… read more here.
Keywords: derived exosome; gut microbiota; exosome like; dietary derived ... See more keywords
Plum-Derived Exosome-like Nanovesicles Induce Differentiation of Osteoblasts and Reduction of Osteoclast Activation
Sign Up to like & getrecommendations! Published in 2023 at "Nutrients"
DOI: 10.3390/nu15092107
Abstract: Osteoblasts and osteoclasts play crucial roles in bone formation and bone resorption. We found that plum-derived exosome-like nanovesicles (PENVs) suppressed osteoclast activation and modulated osteoblast differentiation. PENVs increased the proliferation, differentiation, and mineralization of osteoblastic… read more here.
Keywords: derived exosome; osteoclast activation; exosome like; plum derived ... See more keywords
Tumor-derived Exosome Promotes Metastasis via Altering its Phenotype and Inclusions
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cancer"
DOI: 10.7150/jca.48043
Abstract: Although tumor-derived exosomes play an important role in the process of metastasis, differences in exosomes secreted by the same cells at different stages or conditions have not been noticed by most of the relevant researchers.… read more here.
Keywords: derived exosome; exosome promotes; tumor derived; cancer ... See more keywords