Viola Yedoensis Makino‐Derived Exosome‐Like Nanovesicles‐Loaded Adhesive Promotes Diabetic Fracture Healing via Anti‐Inflammatory Properties
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202501742
Abstract: Fracture management in patients with diabetes mellitus presents a significant clinical challenge, often resulting in nonunion or delayed fracture healing due to dysregulation of macrophage polarization and a persistent inflammatory microenvironment. While traditional internal fixation… read more here.
Keywords: yedoensis makino; fracture; derived exosome; makino derived ... See more keywords
ROS-responsive MSC-derived Exosome Mimetics Carrying MHY1485 Alleviate Renal Ischemia Reperfusion Injury through Multiple Mechanisms
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DOI: 10.1021/acsomega.4c01624
Abstract: Renal ischemia reperfusion (IR) injury is a prevalent inflammatory nephropathy in surgeries such as renal transplantation or partial nephrectomy, damaging renal function through inducing inflammation and cell death in renal tubules. Mesenchymal stromal/stem cell (MSC)-based… read more here.
Keywords: renal ischemia; ischemia reperfusion; derived exosome; reperfusion injury ... See more keywords
Therapeutic potential of plant-derived exosome-like nanoparticles for CNS diseases: advancements in preparation and characterization
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DOI: 10.1080/07853890.2025.2537345
Abstract: Abstract Background: Central nervous system (CNS) diseases pose significant therapeutic challenges owing to their complex pathophysiology and the restrictive nature of the blood-brain barrier (BBB). Introduction: Plant-derived exosome-like nanoparticles (PDELNs) exhibit intrinsic bioactivity, low immunogenicity,… read more here.
Keywords: derived exosome; plant; exosome like; plant derived ... See more keywords
Application of plant-derived exosome-like nanoparticles in drug delivery
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2023.2202242
Abstract: Abstract Exosomes are one type of extracellular vesicles with size ranging from 30 to 150 nm, which are involved in intercellular communication by transporting specific proteins, nucleic acids, and low molecular weight metabolites. The size and… read more here.
Keywords: derived exosome; exosome like; drug delivery; plant derived ... See more keywords
Photinia glabra-derived exosome-like nanovesicles mitigate skin inflammaging via dual regulation of inflammatory signaling and calcium homeostasis
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DOI: 10.1080/17435889.2025.2572991
Abstract: ABSTRACT Aims Chronic low-grade inflammation accelerates skin aging, termed inflammaging. This study investigates whether Photinia glabra-derived exosome-like nanovesicles (PgELNs) can alleviate inflammaging by modulating inflammatory signaling and calcium homeostasis. Materials and methods PgELNs were isolated… read more here.
Keywords: glabra derived; derived exosome; calcium homeostasis; calcium ... See more keywords
Enhancing Functional Recovery after Segmental Nerve Defect using Nerve Allograft treated with Plasma-Derived Exosome.
Sign Up to like & getrecommendations! Published in 2023 at "Plastic and reconstructive surgery"
DOI: 10.1097/prs.0000000000010389
Abstract: BACKGROUND Nerve injuries can result in detrimental functional outcomes. Currently, autologous nerve graft offers the best outcome for segmental peripheral nerve injury. Allografts are alternatives, but do not have comparable results. This study evaluated if… read more here.
Keywords: derived exosome; nerve; functional recovery; plasma derived ... See more keywords
Abstract 2349: Investigating the effect of ECM stiffness on macrophage-derived exosome secretion and PDAC organoid progression
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-2349
Abstract: Pancreatic ductal adenocarcinoma (PDAC) has a 5-year survival rate of only 11%. Current treatments that mostly target the cancer cells themselves, have not been able to significantly improve survival rates, meaning there is an urgent… read more here.
Keywords: ecm stiffness; derived exosome; exosome secretion; macrophage derived ... See more keywords
Momordica charantia L.-derived exosome-like nanovesicles stabilize p62 expression to ameliorate doxorubicin cardiotoxicity
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Nanobiotechnology"
DOI: 10.1186/s12951-024-02705-z
Abstract: Doxorubicin (DOX) is a first-line chemotherapeutic drug for various malignancies that causes cardiotoxicity. Plant-derived exosome-like nanovesicles (P-ELNs) are growing as novel therapeutic agents. Here, we investigated the protective effects in DOX cardiotoxicity of ELNs from… read more here.
Keywords: derived exosome; cardiotoxicity; exosome like; like nanovesicles ... See more keywords
Therapeutic effect of mesenchymal stem cell-derived exosome therapy for periodontal regeneration: a systematic review and meta-analysis of preclinical trials
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DOI: 10.1186/s13018-024-05403-6
Abstract: To assess the therapeutic effects of mesenchymal stem cell (MSC)-derived exosome therapy on periodontal regeneration and identify treatment factors associated with enhanced periodontal regeneration in recent preclinical studies. Searches were conducted in PubMed, Cochrane Library,… read more here.
Keywords: derived exosome; mesenchymal stem; periodontal regeneration; exosome therapy ... See more keywords
Isolation of plant-derived exosome-like nanoparticles (PDENs) from Solanum nigrum L. berries and Their Effect on interleukin-6 expression as a potential anti-inflammatory agent
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DOI: 10.1371/journal.pone.0296259
Abstract: Inflammation is a temporary response of the immune system that can be treated using common anti-inflammatory drugs. However, prolonged use of these drugs increases the risk of adverse side effects. Accordingly, there is an increasing… read more here.
Keywords: derived exosome; exosome like; plant derived; like nanoparticles ... See more keywords
Designing a Multiple-Epitope Vaccine Candidate against Leishmania major and Leishmania infantum for Monocyte-Derived Exosome Preparation
Sign Up to like & getrecommendations! Published in 2024 at "Iranian Journal of Parasitology"
DOI: 10.18502/ijpa.v19i2.15851
Abstract: Background: Leishmania is a vector-borne protozoon, which causes visceral, cutaneous and mucocutaneous leishmaniosis in human and animals. Monocyte-derived exosome vaccines can be used as prophylaxis and immunotherapy strategies. The aim of this study was to… read more here.
Keywords: derived exosome; monocyte derived; multiple epitope; leishmania ... See more keywords