Functional Immune Cell‐Derived Exosomes Engineered for the Trilogy of Radiotherapy Sensitization
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202106031
Abstract: The limited efficacy of radiotherapy leads to radio‐resistance and high rates of tumor recurrence and metastasis, which is caused by tumor hypoxia, rapid DNA damage repair, and especially the suppressive immune microenvironment of tumor. Lots… read more here.
Keywords: derived exosomes; immune cell; trilogy radiotherapy; radiotherapy ... See more keywords
SARS‐CoV‐2 and Mitochondrial Proteins in Neural‐Derived Exosomes of COVID‐19
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26350
Abstract: As SARS‐CoV‐2 is known to invade neural cell mitochondria, a plasma system for quantifying central nervous system proteins in living humans was used to investigate neuropathogenic mechanisms of long‐COVID‐19. read more here.
Keywords: cov mitochondrial; neural derived; derived exosomes; mitochondrial proteins ... See more keywords
Parkinson's Disease Derived Exosomes Aggravate Neuropathology in SNCA*A53T Mice
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Neurology"
DOI: 10.1002/ana.26421
Abstract: Accumulation of α‐synuclein (α‐syn) in neurons is a prominent feature of Parkinson's disease (PD). Recently, researchers have considered that extracellular vesicles (EVs) may play an important role in protein exportation and propagation, and α‐syn‐containing EVs… read more here.
Keywords: exosomes aggravate; derived exosomes; disease; parkinson disease ... See more keywords
Hypoxia preconditioned mesenchymal stem cell-derived exosomes induce ex vivo expansion of umbilical cord blood hematopoietic stem cells CD133+ by stimulation of Notch signalling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology progress"
DOI: 10.1002/btpr.3222
Abstract: Mesenchymal stem cells (MSCs) are crucial cells that play an essential role in the maintenance, self-renewal, and proliferation of hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) in the bone marrow niche. It has… read more here.
Keywords: hscs; hematopoietic stem; msc; stem ... See more keywords
The homologous tumor‐derived‐exosomes loaded with miR‐1270 selectively enhanced the suppression effect for colorectal cancer cells
Sign Up to like & getrecommendations! Published in 2024 at "Cancer Medicine"
DOI: 10.1002/cam4.6936
Abstract: Colorectal cancer (CRC), known as prevalent cancer, has risen to be the leading cause of cancer‐related death. Engineered exosomes had attracted much attention since they acted as carriers to deliver small molecule drugs, therapeutic nucleic… read more here.
Keywords: colorectal cancer; cancer; homologous tumor; tumor derived ... See more keywords
Leukemia cancer cells and immune cells derived‐exosomes: Possible roles in leukemia progression and therapy
Sign Up to like & getrecommendations! Published in 2024 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3960
Abstract: Exosomes have a significant impact on tumor survival, proliferation, metastasis, and recurrence. They also open up new therapeutic options and aid in the pathological identification and diagnosis of cancers. Exosomes have been shown in numerous… read more here.
Keywords: immune cells; cancer cells; derived exosomes; leukemia ... See more keywords
Exosomes to control glioblastoma multiforme: Investigating the effects of mesenchymal stem cell‐derived exosomes on C6 cells in vitro
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11884
Abstract: Glioblastoma multiforme (GBM) is a common, aggressive, fast‐growing tumor of the central nervous system that currently has no effective treatment. Although stem cell therapy has shown promising in vitro achievements, the blood–brain barrier (BBB) has… read more here.
Keywords: cell; stem cell; derived exosomes; mesenchymal stem ... See more keywords
Using Natural Killer Cell-derived Exosomes as a Cell-Free Therapy for Leukemia.
Sign Up to like & getrecommendations! Published in 2022 at "Hematological oncology"
DOI: 10.1002/hon.3111
Abstract: Natural killer (NK) cells are components of the innate immune system which play a pivotal role in cancer cell surveillance. Despite promising results in clinical trials, the use of NK-based therapies is limited due to… read more here.
Keywords: cell; derived exosomes; natural killer; leukemia ... See more keywords
Characterization and proteomic profiling of pancreatic cancer‐derived serum exosomes
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27465
Abstract: Pancreatic cancer (PC) is one of the most lethal cancers known worldwide, and its prognosis is poor in most patients. Exosomes are nanosized extracellular vesicles, which are released from various cell types. They are involved… read more here.
Keywords: characterization proteomic; exosomes derived; pancreatic cancer; derived exosomes ... See more keywords
The role of stem cell-derived exosomes in the repair of cutaneous and bone tissue.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30144
Abstract: Exosomes are extracellular vesicles secreted by various cell types, which play important roles in physiological processes. In particular, stem cell-derived exosomes have been shown to play crucial functions in intercellular communication during the tissue healing… read more here.
Keywords: cell derived; tissue; bone; stem cell ... See more keywords
Breast cancer‐derived exosomes: Tumor progression and therapeutic agents
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29668
Abstract: Tumor cells secrete extracellular vesicles (EVs) for intercellular communication. EVs by transporting different proteins, nucleic acids, and lipids contribute to affect target cell function and fate. EVs which originate directly from multivesicular bodies so‐called exosomes… read more here.
Keywords: tumor progression; breast cancer; cancer derived; cancer ... See more keywords