Cognitive Resilience in Apolipoprotein ε4 Carrier Women Predicted by Neuron‐Derived Extracellular Vesicles
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.70143
Abstract: The Apolipoprotein (APOE) ε4 allele is the strongest genetic risk factor for late‐onset Alzheimer's disease (AD); however, many ε4 carriers remain cognitively intact into old age. Leveraging plasma neuron‐derived extracellular vesicles (NDEVs), we sought to… read more here.
Keywords: extracellular vesicles; derived extracellular; cognitive resilience; resilience apolipoprotein ... See more keywords
Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced functional materials"
DOI: 10.1002/adfm.202003237
Abstract: Tumor-derived extracellular vesicles (EVs) play essential roles in intercellular communication during tumor growth and metastatic evolution. Currently, little is known about the possible roles of tumor-derived EVs in sarcoma because the lack of specific surface… read more here.
Keywords: sarcoma; extracellular vesicles; chemistry; derived extracellular ... See more keywords
Nasal Mucosa-Derived Extracellular Vesicles as a Systemic Antiaging Intervention.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced science"
DOI: 10.1002/advs.202511372
Abstract: Aging impairs tissue function and regenerative capacity across multiple organs. This study demonstrates that extracellular vesicles derived from human nasal mucosa (nmEVs) exert systemic antiaging effects in aged mice. Treatment with nmEVs improves cognitive performance… read more here.
Keywords: extracellular vesicles; mucosa derived; nasal mucosa; systemic antiaging ... See more keywords
Fibroblast‐Derived Extracellular Vesicles Ameliorate the Skin Injury Microenvironment to Promote Wound Healing
Sign Up to like & getrecommendations! Published in 2025 at "Cell Biology International"
DOI: 10.1002/cbin.70063
Abstract: Fibroblasts are pivotal cellular components in cutaneous wound healing and are regarded as promising therapeutic candidates. However, their functional heterogeneity within tissue microenvironments significantly limits their clinical application. In contrast, whether fibroblast‐derived extracellular vesicles (EVs)… read more here.
Keywords: extracellular vesicles; hdf evs; fibroblast; derived extracellular ... See more keywords
Stimulus‐dependent modifications in astrocyte‐derived extracellular vesicle cargo regulate neuronal excitability
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23708
Abstract: Extracellular vesicles have now emerged as key players in cell‐to‐cell communication. This is particularly important in the central nervous system, where glia–neuron cross‐talk helps maintain normal neuronal function. Astrocyte‐derived extracellular vesicles (ADEVs) secreted constitutively promote… read more here.
Keywords: response; stimulus; adevs secreted; derived extracellular ... See more keywords
Lung mechanics modifications facilitating metastasis are mediated in part by breast cancer‐derived extracellular vesicles
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33229
Abstract: Tumor microenvironment‐mechanics greatly affect tumor‐cell characteristics such as invasion and proliferation. We and others have previously shown that after chemotherapy, tumor cells shed more extracellular vesicles (EVs), leading to tumor growth and even spread, via… read more here.
Keywords: extracellular vesicles; metastasis; derived extracellular; cancer ... See more keywords
Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12197
Abstract: Abstract Tumour‐draining lymph nodes (LNs) undergo massive remodelling including expansion of the lymphatic sinuses, a process that has been linked to lymphatic metastasis by creation of a pre‐metastatic niche. However, the signals leading to these… read more here.
Keywords: derived extracellular; extracellular vesicles; vesicles mediate; draining lymph ... See more keywords
Tumour‐derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour‐homing and intracellular freeway transportation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12198
Abstract: Abstract Extracellular vesicles (EVs) have been proved a promising small interfering RNA (siRNA) delivery vehicle to mediate gene‐silencing. Tumour‐derived extracellular vesicles (TDEVs) as genetic exchange vectors in the tumour microenvironment, enable intercellular communication for a… read more here.
Keywords: derived extracellular; tumour derived; membrane; delivery ... See more keywords
A new strategy to count and sort neutrophil-derived extracellular vesicles: Validation in infectious disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of extracellular vesicles"
DOI: 10.1002/jev2.12204
Abstract: Newly recognized polymorphonuclear neutrophil (PMNs) functions include the ability to release subcellular mediators such as neutrophil-derived extracellular vesicles (NDEVs) involved in immune and thrombo-inflammatory responses. Elevation of their plasmatic level has been reported in a… read more here.
Keywords: neutrophil derived; strategy count; strategy; derived extracellular ... See more keywords
Milk‐derived extracellular vesicles functionalized with anti‐tumour necrosis factor‐α nanobody and anti‐microbial peptide alleviate ulcerative colitis in mice
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12462
Abstract: Abstract Ulcerative colitis (UC) manifests clinically with chronic intestinal inflammation and microflora dysbiosis. Although biologics can effectively control inflammation, efficient delivery to the colon and colon epithelial cells remains challenging. Milk‐derived extracellular vesicles (EV) show… read more here.
Keywords: extracellular vesicles; tumour necrosis; milk derived; derived extracellular ... See more keywords
Roseburia intestinalis‐derived extracellular vesicles ameliorate colitis by modulating intestinal barrier, microbiome, and inflammatory responses
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12487
Abstract: Abstract Inflammatory bowel disease (IBD) is a chronic disorder characterized by recurrent gastrointestinal inflammation, lacking a precise aetiology and definitive cure. The gut microbiome is vital in preventing and treating IBD due to its various… read more here.
Keywords: extracellular vesicles; intestinalis derived; gut microbiome; derived extracellular ... See more keywords