Coupling Nanostructured Microchips with Covalent Chemistry Enables Purification of Sarcoma-Derived Extracellular Vesicles for Downstream Functional Studies.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced functional materials"
DOI: 10.1002/adfm.202003237
Abstract: Tumor-derived extracellular vesicles (EVs) play essential roles in intercellular communication during tumor growth and metastatic evolution. Currently, little is known about the possible roles of tumor-derived EVs in sarcoma because the lack of specific surface… read more here.
Keywords: sarcoma; extracellular vesicles; chemistry; derived extracellular ... See more keywords
Stimulus‐dependent modifications in astrocyte‐derived extracellular vesicle cargo regulate neuronal excitability
Sign Up to like & getrecommendations! Published in 2019 at "Glia"
DOI: 10.1002/glia.23708
Abstract: Extracellular vesicles have now emerged as key players in cell‐to‐cell communication. This is particularly important in the central nervous system, where glia–neuron cross‐talk helps maintain normal neuronal function. Astrocyte‐derived extracellular vesicles (ADEVs) secreted constitutively promote… read more here.
Keywords: response; stimulus; adevs secreted; derived extracellular ... See more keywords
Lung mechanics modifications facilitating metastasis are mediated in part by breast cancer‐derived extracellular vesicles
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Cancer"
DOI: 10.1002/ijc.33229
Abstract: Tumor microenvironment‐mechanics greatly affect tumor‐cell characteristics such as invasion and proliferation. We and others have previously shown that after chemotherapy, tumor cells shed more extracellular vesicles (EVs), leading to tumor growth and even spread, via… read more here.
Keywords: extracellular vesicles; metastasis; derived extracellular; cancer ... See more keywords
Melanoma‐derived extracellular vesicles mediate lymphatic remodelling and impair tumour immunity in draining lymph nodes
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12197
Abstract: Abstract Tumour‐draining lymph nodes (LNs) undergo massive remodelling including expansion of the lymphatic sinuses, a process that has been linked to lymphatic metastasis by creation of a pre‐metastatic niche. However, the signals leading to these… read more here.
Keywords: derived extracellular; extracellular vesicles; vesicles mediate; draining lymph ... See more keywords
Tumour‐derived extracellular vesicle membrane hybrid lipid nanovesicles enhance siRNA delivery by tumour‐homing and intracellular freeway transportation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12198
Abstract: Abstract Extracellular vesicles (EVs) have been proved a promising small interfering RNA (siRNA) delivery vehicle to mediate gene‐silencing. Tumour‐derived extracellular vesicles (TDEVs) as genetic exchange vectors in the tumour microenvironment, enable intercellular communication for a… read more here.
Keywords: derived extracellular; tumour derived; membrane; delivery ... See more keywords
A new strategy to count and sort neutrophil-derived extracellular vesicles: Validation in infectious disorders.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of extracellular vesicles"
DOI: 10.1002/jev2.12204
Abstract: Newly recognized polymorphonuclear neutrophil (PMNs) functions include the ability to release subcellular mediators such as neutrophil-derived extracellular vesicles (NDEVs) involved in immune and thrombo-inflammatory responses. Elevation of their plasmatic level has been reported in a… read more here.
Keywords: neutrophil derived; strategy count; strategy; derived extracellular ... See more keywords
α‐Synuclein in Plasma‐Derived Extracellular Vesicles Is a Potential Biomarker of Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2021 at "Movement Disorders"
DOI: 10.1002/mds.28639
Abstract: Extracellular vesicles are small vesicles that are released from many cells, including neurons. α‐Synuclein has recently been described in extracellular vesicles derived from the central nervous system and may contribute to the spreading of disease… read more here.
Keywords: extracellular vesicles; vesicles potential; derived extracellular; synuclein plasma ... See more keywords
Functional dosing of mesenchymal stromal cell‐derived extracellular vesicles for the prevention of acute graft‐versus‐host‐disease
Sign Up to like & getrecommendations! Published in 2020 at "STEM CELLS"
DOI: 10.1002/stem.3160
Abstract: Graft‐vs‐host‐disease (GvHD) is currently the main complication of allogeneic hematopoietic stem cell transplantation. Mortality and morbidity rates are particularly high, especially in steroid‐refractory acute GvHD (aGvHD). Immune regulatory human bone marrow mesenchymal stromal cells (hMB‐MSCs)… read more here.
Keywords: extracellular vesicles; mesenchymal stromal; hbm msc; graft ... See more keywords
The impact of obesity on adipocyte-derived extracellular vesicles
Sign Up to like & getrecommendations! Published in 2021 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-021-03973-w
Abstract: Recently, the emerging roles of adipocyte-derived extracellular vesicles (EVs) linking obesity and its comorbidities have been recognized. In obese subjects, adipocytes are having hypertrophic growth and are under stressed. The dysfunction adipocytes dysregulate the assembly… read more here.
Keywords: extracellular vesicles; impact obesity; adipocyte derived; derived extracellular ... See more keywords
Tumor-derived extracellular vesicles: insights into bystander effects of exosomes after irradiation
Sign Up to like & getrecommendations! Published in 2019 at "Lasers in Medical Science"
DOI: 10.1007/s10103-019-02880-8
Abstract: This review article aims to address the kinetic of TDEs in cancer cells pre- and post-radiotherapy. Radiotherapy is traditionally used for the treatment of multiple cancer types; however, there is growing evidence to show that… read more here.
Keywords: extracellular vesicles; tumor; radiotherapy; tumor derived ... See more keywords
Protein disulfide isomerase family A member 3 expression is upregulated in tissue-derived extracellular vesicles in oral lichen planus and oral lichenoid lesions.
Sign Up to like & getrecommendations! Published in 2022 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2022.105390
Abstract: OBJECTIVES The aim of this study was to identify the tissue-derived extracellular vesicles immunogen involved in the pathogenesis of oral lichen planus (OLP) and its variation oral lichenoid lesions (OLL). DESIGN Six pooled tissue-derived extracellular… read more here.
Keywords: oral lichen; oral lichenoid; tissue derived; derived extracellular ... See more keywords