Human pancreatic tumour organoid‐derived factors enhance myogenic differentiation
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.12917
Abstract: Most patients with pancreatic cancer develop cachexia, which is characterized by progressive muscle loss. The mechanisms underlying muscle loss in cancer cachexia remain elusive. Pancreatic tumour organoids are 3D cell culture models that retain key… read more here.
Keywords: tumour organoid; pancreatic tumour; muscle; tumour ... See more keywords
Molecular Mechanisms Responsible for Anti-inflammatory and Immunosuppressive Effects of Mesenchymal Stem Cell-Derived Factors.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/5584_2018_306
Abstract: Mesenchymal stem cells (MSCs) are self-renewable cells capable for multilineage differentiation and immunomodulation. MSCs are able to differentiate into all cell types of mesodermal origin and, due to their plasticity, may generate cells of neuroectodermal… read more here.
Keywords: medicine; mechanisms responsible; molecular mechanisms; cell ... See more keywords
Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-10646-7
Abstract: Recently our groups discovered lugdunin, a new cyclic peptide antibiotic that inhibits Staphylococcus aureus epithelial colonization in humans and rodents. In this work, we analyzed its immuno-modulatory and antimicrobial potential as a single agent or… read more here.
Keywords: microbiota; derived factors; keratinocytes mouse; host ... See more keywords
Human Bronchial Epithelial Cell‐derived Factors from Severe Asthmatic Subjects Stimulate Eosinophil Differentiation
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Respiratory Cell and Molecular Biology"
DOI: 10.1165/rcmb.2016-0262oc
Abstract: &NA; Activated bronchial epithelial cells (BEC) release various alarmins, including thymic stromal lymphopoietin (TSLP), that drive type 2 inflammation. We hypothesize that BEC‐derived factors promote in situ eosinophil differentiation and maturation, a process that is… read more here.
Keywords: bronchial epithelial; human bronchial; cell; derived factors ... See more keywords
Saphenous Vein Vasa Vasorum as a Potential Target for Perivascular Fat-Derived Factors
Sign Up to like & getrecommendations! Published in 2020 at "Brazilian Journal of Cardiovascular Surgery"
DOI: 10.21470/1678-9741-2020-0031
Abstract: Perivascular adipose tissue (PVAT) is a source of factors affecting vasomotor tone with the potential to play a role in the performance of saphenous vein (SV) bypass grafts. As these factors have been described as… read more here.
Keywords: potential target; vasa vasorum; vasorum potential; saphenous vein ... See more keywords
Insights on the Role of Putative Muscle-Derived Factors on Pancreatic Beta Cell Function
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.01024
Abstract: Skeletal muscle is a main target of insulin action that plays a pivotal role in postprandial glucose disposal. Importantly, skeletal muscle insulin sensitivity relates inversely with pancreatic insulin secretion, which prompted the hypothesis of the… read more here.
Keywords: skeletal muscle; insulin; muscle; muscle derived ... See more keywords
Blood Pressure-Lowering Effect of Wine Lees Phenolic Compounds Is Mediated by Endothelial-Derived Factors: Role of Sirtuin 1
Sign Up to like & getrecommendations! Published in 2021 at "Antioxidants"
DOI: 10.3390/antiox10071073
Abstract: The antihypertensive effect of wine lees powder (WLPW) from a Cabernet grape variety was related to its high content in flavanols and anthocyanins compounds. This study investigates the involvement of endothelial-derived factors and SIRT1 in… read more here.
Keywords: wine lees; endothelial derived; blood pressure; effect ... See more keywords