Sulfonyl hydrazones derived from 3-formylchromone as non-selective inhibitors of MAO-A and MAO-B: Synthesis, molecular modelling and in-silico ADME evaluation.
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DOI: 10.1016/j.bioorg.2017.10.001
Abstract: A series of sulfonyl hydrazones derived from 3-formylchromone was synthesized and discovered to be effective, non-selective inhibitors of monoamine oxidases (MAO-A and MAO-B). The compounds are easily (synthetically) accessible in high yields, by simple condensation… read more here.
Keywords: sulfonyl hydrazones; hydrazones derived; mao; non selective ... See more keywords