Identification of a fibroblast-derived gene signature reveals prognostic and therapeutic insights in pancreatic cancer
Sign Up to like & getrecommendations! Published in 2025 at "Clinical and Experimental Medicine"
DOI: 10.1007/s10238-025-01801-0
Abstract: Fibroblasts play a crucial role in the progression of pancreatic ductal adenocarcinoma (PDAC). This study aimed to develop a prognostic model based on fibroblast-specific gene signatures and identify key genes that may serve as therapeutic… read more here.
Keywords: identification fibroblast; derived gene; signature; fibroblast derived ... See more keywords
A Cell Cycle Progression-Derived Gene Signature to Predict Prognosis and Therapeutic Response in Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Disease Markers"
DOI: 10.1155/2021/1986159
Abstract: Objective Dysregulation of cell cycle progression (CCP) is one of the hallmarks of cancer. Here, our study is aimed at developing a CCP-derived gene signature for predicting high-risk population of hepatocellular carcinoma (HCC). Methods Our… read more here.
Keywords: derived gene; ccp derived; signature; gene signature ... See more keywords
Genomic Instability of Mutation-Derived Gene Prognostic Signatures for Hepatocellular Carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.728574
Abstract: Hepatocellular carcinoma (HCC) is one of the major cancer-related deaths worldwide. Genomic instability is correlated with the prognosis of cancers. A biomarker associated with genomic instability might be effective to predict the prognosis of HCC.… read more here.
Keywords: hepatocellular carcinoma; prognostic signature; derived gene; genomic instability ... See more keywords
Integrative Analysis Identifies a TNFα-Derived Gene Signature for Predicting Prognosis, Tumor Immunity, and Treatment Sensitivity in Gastric Cancer
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DOI: 10.3389/fgene.2022.882519
Abstract: Objective: TNF-α is an essential pro-inflammatory cytokine in the tumor microenvironment of gastric cancer (GC), possessing a key biological and clinical impact. Here, we conducted an integrative analysis of the role of TNFα-derived genes in… read more here.
Keywords: gene signature; prognosis; derived gene; tnf derived ... See more keywords