The Soluble Platelet‐Derived Growth Factor β Receptor Induces Postoperative Delirium by Downregulating the Clearance of β‐Amyloid in the Brain
Sign Up to like & getrecommendations! Published in 2025 at "Brain and Behavior"
DOI: 10.1002/brb3.70436
Abstract: To investigate the relationship between soluble platelet‐derived growth factor β receptor (sPDGFRβ) in cerebrospinal fluid (CSF) and Alzheimer's disease (AD) biomarkers, to determine whether high CSF sPDGGFRβ is a potential risk factor for postoperative delirium… read more here.
Keywords: derived growth; soluble platelet; factor; factor receptor ... See more keywords
Chimeric antigen receptor‐modified T‐cell therapy for platelet‐derived growth factor receptor α‐positive rhabdomyosarcoma
Sign Up to like & getrecommendations! Published in 2020 at "Cancer"
DOI: 10.1002/cncr.32764
Abstract: New immunotherapeutic approaches are urgently needed for metastatic rhabdomyosarcoma, which is associated with poor survival and unsatisfactory treatment outcomes. Platelet‐derived growth factor receptor α (PDGFRA) plays an essential role in the onset and development of… read more here.
Keywords: growth factor; rhabdomyosarcoma; receptor; factor receptor ... See more keywords
Optimizing esthetic zone periodontal regeneration in a 1–2‐wall infrabony defect using recombinant human platelet‐derived growth factor BB and β‐tricalcium phosphate: A case report
Sign Up to like & getrecommendations! Published in 2024 at "Clinical and Experimental Dental Research"
DOI: 10.1002/cre2.908
Abstract: Periodontitis is an inflammatory condition induced by subgingival bacterial dysbiosis, resulting in inflammatory‐mediated destruction of tooth‐supporting structures, potentially leading to the formation of infrabony defects. This case report describes the treatment of a patient who… read more here.
Keywords: derived growth; case report; recombinant human; using recombinant ... See more keywords
Platelet‐Derived Growth Factor Promotes Glomerular Mesangial Cells Differentiation of Human Bone Marrow Hematopoietic Stem Cells ‐ An In Vitro Study
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.70012
Abstract: Glomerular filtration function and homeostasis are largely due to the cross‐talk between podocytes, endothelial cells, and mesangial cells (MCs). Any disturbance in this association causes glomerular diseases (GD). Cell‐based therapies are the best option in… read more here.
Keywords: derived growth; mcs; mesangial cells; hematopoietic stem ... See more keywords
Correlation between platelet‐derived growth factor‐B gene polymorphism and coronary heart disease
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24683
Abstract: The aim of the present work was to investigate the correlation of plasma platelet‐derived growth factor (PDGF)‐BB level and single nucleotide polymorphism (SNP, rs1800817 and rs2285094) of PDGF‐B gene with the onset and stability condition… read more here.
Keywords: coronary heart; correlation; growth factor; derived growth ... See more keywords
Hepatoma‐derived growth factor is associated with pulmonary vascular remodeling and PAH disease severity and survival
Sign Up to like & getrecommendations! Published in 2022 at "Pulmonary Circulation"
DOI: 10.1002/pul2.12007
Abstract: Abstract Hepatoma‐derived growth factor (HDGF) was previously shown to be associated with increased mortality in a small study of idiopathic and connective tissue disease‐associated pulmonary arterial hypertension (PAH). In this study, we measured serum HDGF… read more here.
Keywords: derived growth; disease; hepatoma derived; hdgf ... See more keywords
Exploring the Impact of Platelet‐Derived Growth Factor D in Pulmonary Hypertension Development
Sign Up to like & getrecommendations! Published in 2025 at "Pulmonary Circulation"
DOI: 10.1002/pul2.70216
Abstract: ABSTRACT Pulmonary arterial hypertension (PAH) is a life‐threatening condition with no cure, making research into its underlying mechanisms critical. The platelet‐derived growth factor (PDGF) signaling pathway plays a crucial role in vascular remodeling, a key… read more here.
Keywords: derived growth; pah; platelet derived; factor ... See more keywords
Platelet-derived growth factor receptor beta identifies mesenchymal stem cells with enhanced engraftment to tissue injury and pro-angiogenic property
Sign Up to like & getrecommendations! Published in 2017 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-017-2641-7
Abstract: Mesenchymal stem cells (MSCs) are heterogeneous likely consisting of subpopulations with various therapeutic potentials. Here we attempted to acquire a subset of MSCs with enhanced effect in wound healing. We found that human placental MSCs… read more here.
Keywords: derived growth; mscs; stem cells; platelet derived ... See more keywords
Ultrastructural and Molecular Characterization of Platelet-derived growth factor Beta-Positive Leptomeningeal Cells in the Adult Rat Brain
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Neurobiology"
DOI: 10.1007/s12035-019-01793-5
Abstract: The leptomeninges, referring to the arachnoid and pia mater and their projections into the perivascular compartments in the central nervous system, actively participate in diverse biological processes including fluid homeostasis, immune cell infiltrations, and neurogenesis,… read more here.
Keywords: pdgfr cells; factor beta; growth factor; pdgfr ... See more keywords
Ligand-based computational modelling of platelet-derived growth factor beta receptor leading to new angiogenesis inhibitory leads
Sign Up to like & getrecommendations! Published in 2017 at "Computational biology and chemistry"
DOI: 10.1016/j.compbiolchem.2017.10.003
Abstract: Platelet derived growth factor beta receptor (PDGFR- β) plays an important role in angiogenesis. PDGFR-β expression is correlated with increased vascularity and maturation of blood vessels in cancer. Pharmacophore modeling and quantitative structure-activity relationship (QSAR)… read more here.
Keywords: angiogenesis; factor beta; beta receptor; growth factor ... See more keywords
Plasma Concentrations of Myeloid-Derived Growth Factor in Healthy Individuals and Patients with Acute Myocardial Infarction as Assessed by Multiple Reaction Monitoring-Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.8b03041
Abstract: Myeloid-derived growth factor (MYDGF in humans, Mydgf in mice) is a secreted protein with previously unknown biological functions. In a recent study, Mydgf was shown to mediate cardiac repair after acute myocardial infarction (MI) in… read more here.
Keywords: patients acute; myocardial infarction; growth factor; acute myocardial ... See more keywords