Experimental and Computational Evaluation of Piperonylic Acid Derived Hydrazones Bearing Isatin Moieties as Dual Inhibitors of Cholinesterases and Monoamine Oxidases
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DOI: 10.1002/cmdc.201900277
Abstract: A set of piperonylic acid derived hydrazones with variable isatin moieties was synthesized and evaluated for their inhibitory activity against the enzymes acetylcholinesterase (AChE), butyrylcholinesterase (BChE), and monoamine oxidases A and B (MAO‐A/B). The results… read more here.
Keywords: derived hydrazones; acid derived; isatin moieties; piperonylic acid ... See more keywords
Silver(I) complexes with chromone-derived hydrazones: investigation on the antimicrobial and cytotoxic effects
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DOI: 10.1007/s10534-017-0013-2
Abstract: Complexes [Ag(HCrPh)2]NO3·2H2O (1) and [Ag(HCrpClPh)2]NO3 (2) were obtained with 3-formyl-6-methylchromone-phenyl hydrazone (HCrPh, HL1) and 3-formyl-6-methylchromone-para-chloro-phenyl hydrazone (HCrpClPh, HL2). Although the hydrazones were inactive, upon coordination to silver(I) antifungal activity significantly improved against several Candida strains.… read more here.
Keywords: derived hydrazones; cytotoxic; silver complexes; chromone derived ... See more keywords