Bone marrow-derived IGF-1 orchestrates maintenance and regeneration of the adult skeleton.
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DOI: 10.1073/pnas.2203779120
Abstract: Insulin-like growth factor I (IGF-1) is a key regulator of tissue growth and development in response to growth hormone stimulation. In the skeletal system, IGF-1 derived from osteoblasts and chondrocytes are essential for normal bone… read more here.
Keywords: regeneration; bone; marrow; adult skeleton ... See more keywords