Neurotrophically Induced Mesenchymal Progenitor Cells Derived from Induced Pluripotent Stem Cells Enhance Neuritogenesis via Neurotrophin and Cytokine Production
Sign Up to like & getrecommendations! Published in 2018 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.17-0108
Abstract: Adult tissue‐derived mesenchymal stem cells (MSCs) are known to produce a number of bioactive factors, including neurotrophic growth factors, capable of supporting and improving nerve regeneration. However, with a finite culture expansion capacity, MSCs are… read more here.
Keywords: medicine; derived induced; pluripotent stem; induced pluripotent ... See more keywords
A scalable system for generation of mesenchymal stem cells derived from induced pluripotent cells employing bioreactors and degradable microcarriers.
Sign Up to like & getrecommendations! Published in 2021 at "Stem cells translational medicine"
DOI: 10.1002/sctm.21-0151
Abstract: Human mesenchymal stem cells (hMSCs) are effective in treating disorders resulting from an inflammatory or heightened immune response. The hMSCs derived from induced pluripotent stem cells (ihMSCs) share the characteristics of tissue derived hMSCs but… read more here.
Keywords: ihmscs; induced pluripotent; derived induced; stem ... See more keywords
Mesenchymal stem cells derived from induced pluripotent stem cells play a key role in immunomodulation during cardiopulmonary resuscitation
Sign Up to like & getrecommendations! Published in 2019 at "Brain Research"
DOI: 10.1016/j.brainres.2019.06.012
Abstract: BACKGROUND /Aims Previous in vitro experiments have demonstrated the immunomodulatory functions of mesenchymal stem cells derived from induced pluripotent stem cells (iPSC-MSCs) in brain injury. We have tried to further understand these functions by investigating… read more here.
Keywords: cells derived; group; derived induced; stem ... See more keywords
Modeling neurodegenerative diseases with patient-derived induced pluripotent cells: Possibilities and challenges.
Sign Up to like & getrecommendations! Published in 2017 at "New biotechnology"
DOI: 10.1016/j.nbt.2017.05.009
Abstract: The rising prevalence of progressive neurodegenerative diseases coupled with increasing longevity poses an economic burden at individual and societal levels. There is currently no effective cure for the majority of neurodegenerative diseases and disease-affected tissues… read more here.
Keywords: diseases patient; derived induced; neurodegenerative diseases; modeling neurodegenerative ... See more keywords
Isolated Mitochondria Transfer Improves Neuronal Differentiation of Schizophrenia-Derived Induced Pluripotent Stem Cells and Rescues Deficits in a Rat Model of the Disorder
Sign Up to like & getrecommendations! Published in 2018 at "Schizophrenia Bulletin"
DOI: 10.1093/schbul/sbx077
Abstract: Dysfunction of mitochondria, key players in various essential cell processes, has been repeatedly reported in schizophrenia (SZ). Recently, several studies have reported functional recovery and cellular viability following mitochondrial transplantation, mostly in ischemia experimental models.… read more here.
Keywords: derived induced; model; pluripotent stem; ian mit ... See more keywords
Reduced expression of somatostatin in GABAergic interneurons derived from induced pluripotent stem cells of patients with parkin mutations
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Brain"
DOI: 10.1186/s13041-019-0426-7
Abstract: Parkinson’s disease (PD) is associated with both motor and non-motor symptoms, including constipation, sensory neuropathy, depression, dementia and sleep disorder. Somatostatin (SST) is considered to be a modulator of GABAergic inhibitory transmission, and its levels… read more here.
Keywords: induced pluripotent; expression; pluripotent stem; derived induced ... See more keywords
Studying Abnormal Chromosomal Diseases Using Patient-Derived Induced Pluripotent Stem Cells
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2020.00224
Abstract: Chromosomal abnormality causes congenital and acquired intractable diseases. In general, there are no fundamental treatments for these diseases. To establish platforms to develop therapeutics for these diseases, patient-derived induced pluripotent stem cells (iPSCs) are highly… read more here.
Keywords: induced pluripotent; pluripotent stem; derived induced; abnormal chromosomal ... See more keywords