Retinoic acid promotes barrier functions in human iPSC-derived intestinal epithelial monolayers.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmacological sciences"
DOI: 10.1016/j.jphs.2019.06.012
Abstract: Vitamin A (VA) is a fat-soluble micronutrient that plays essential roles in various biological processes, including cell growth, differentiation, and apoptosis. In the intestine, VA are known to promote mucosal homeostasis and immunity. However, the… read more here.
Keywords: intestinal epithelial; derived intestinal; promotes barrier; epithelial monolayers ... See more keywords
Coculture with hiPS-derived intestinal cells enhanced human hepatocyte functions in a pneumatic-pressure-driven two-organ microphysiological system
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-84861-y
Abstract: Examining intestine–liver interactions is important for achieving the desired physiological drug absorption and metabolism response in in vitro drug tests. Multi-organ microphysiological systems (MPSs) constitute promising tools for evaluating inter-organ interactions in vitro. For coculture… read more here.
Keywords: pneumatic pressure; organ microphysiological; derived intestinal; intestinal cells ... See more keywords
Dual Role of Indoles Derived From Intestinal Microbiota on Human Health
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.903526
Abstract: Endogenous indole and its derivatives (indoles), considered as promising N-substituted heterocyclic compounds, are tryptophan metabolites derived from intestinal microbiota and exhibit a range of biological activities. Recent studies indicate that indoles contribute to maintaining the… read more here.
Keywords: health; intestinal microbiota; derived intestinal; human health ... See more keywords