Cinchona Alkaloid Derived Iodide Catalyzed Enantioselective Oxidative α-Amination of Carbonyl Compounds toward the Construction of Spiroindolyloxindole.
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DOI: 10.1021/acs.orglett.1c04118
Abstract: Novel cinchona alkaloid derived iodide catalysts were developed for the enantioselective oxidative α-amination of 2-oxindoles, providing various functionalized spiropyrrolidine oxindoles in high yields and with good enantioselectivities. This iodide/ROOH catalytic system features a one-step synthesis… read more here.
Keywords: cinchona alkaloid; enantioselective oxidative; oxidative amination; alkaloid derived ... See more keywords