Laminin-511-derived recombinant fragment and Rho kinase inhibitor Y-27632 facilitate serial cultivation of keratinocytes differentiated from human embryonic stem cells
Sign Up to like & getrecommendations! Published in 2021 at "Regenerative Therapy"
DOI: 10.1016/j.reth.2021.07.004
Abstract: Introduction Keratinocytes derived from pluripotent stem cells have a short proliferative lifespan under conventional culture conditions that are optimized for keratinocytes. Recently, a Rho kinase inhibitor, Y-27632, had been used as a standard supplement for… read more here.
Keywords: serial cultivation; laminin 511; derived keratinocytes; cultivation ... See more keywords
Effect of iPSCs-derived keratinocytes on healing of full-thickness skin wounds in mice.
Sign Up to like & getrecommendations! Published in 2019 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2019.111627
Abstract: Induced pluripotent stem cells (iPSCs) provide new approaches for the management of severe skin wound healing due to their infinite proliferative capacity, pluripotency into multiple lineages, and important ethical acceptability. In this study, we aimed… read more here.
Keywords: thickness skin; ipscs derived; full thickness; derived keratinocytes ... See more keywords