Does shuttling of glycogenâderived lactate from astrocytes to neurons take place during neurotransmission and memory consolidation?
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Neuroscience Research"
DOI: 10.1002/jnr.24387
Abstract: Glycogen levels in resting brain and its utilization rates during brain activation are high, but the functions fulfilled by glycogenolysis in living brain are poorly understood. Studies in cultured astrocytes have identified glycogen as the… read more here.
Keywords: glycogen derived; glycogen; derived lactate; neurotransmission ... See more keywords
Tumor-derived lactate inhibit the efficacy of lenvatinib through regulating PD-L1 expression on neutrophil in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Journal for Immunotherapy of Cancer"
DOI: 10.1136/jitc-2020-002305
Abstract: Background Neutrophils play a controversial role in tumor development. The function of programmed cell death-1 ligand (PD-L1+) neutrophils, however, may inhibit the cytotoxicity of anti-tumor immunity. In this study, we elucidate the stimulators of PD-L1+… read more here.
Keywords: hepatocellular carcinoma; derived lactate; tumor derived; expression ... See more keywords
Blastocyst-Derived Lactate as a Key Facilitator of Implantation
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DOI: 10.3390/biom15010100
Abstract: The blastocyst develops a unique metabolism that facilitates the creation of a specialized microenvironment at the site of implantation characterized by high levels of lactate and reduced pH. While historically perceived as a metabolic waste… read more here.
Keywords: blastocyst; key facilitator; derived lactate; implantation ... See more keywords