HPPO-Derived Meroterpenoids from the Marine-Derived Fungus Penicillium sp. SCSIO 41691.
Sign Up to like & getrecommendations! Published in 2024 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.3c01121
Abstract: Seven new 4-hydroxy-6-phenyl-2H-pyran-2-one (HPPO) derived meroterpenoids, 1-methyl-12a,12b-epoxyarisugacin M (1), 1-methyl-4a,12b-epoxyarisugacin M (2), 2,3-dihydroxy-3,4a-epoxy-12a-dehydroxyisoterreulactone A (3), 2-hydroxy-12a-dehydroxyisoterreulactone A (4), 3'-demethoxyterritrems B' (5), 4a-hydroxyarisugacin P (6), and 1-epi-arisugacin H (7), together with two known analogues (8 and… read more here.
Keywords: penicillium scsio; marine derived; hppo derived; derived meroterpenoids ... See more keywords
Total Synthesis of DMOA-Derived Meroterpenoids: Achieving Selectivity in the Synthesis of (+)-Berkeleyacetal D and (+)-Peniciacetal I.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.4c15205
Abstract: The synthesis of complex natural products requires efficient control over chemoselectivity, stereoselectivity, and regioselectivity. Berkeleyacetals, a subfamily of 3,5-dimethylorsellinic acid (DMOA)-derived meroterpenoids, pose substantial synthetic challenges due to their densely functionalized and highly oxidized architectures,… read more here.
Keywords: total synthesis; derived meroterpenoids; dmoa derived; synthesis ... See more keywords
Production of non-natural 5-methylorsellinate-derived meroterpenoids in Aspergillus oryzae
Sign Up to like & getrecommendations! Published in 2024 at "Beilstein Journal of Organic Chemistry"
DOI: 10.3762/bjoc.20.56
Abstract: Fungal meroterpenoids are diverse structurally intriguing molecules with various biological properties. One large group within this compound class is derived from the aromatic precursor 3,5-dimethylorsellinic acid (DMOA). In this study, we constructed engineered metabolic pathways… read more here.
Keywords: non natural; derived meroterpenoids; natural methylorsellinate; methylorsellinate derived ... See more keywords