A Review of Gut Microbiota‐Derived Metabolites in Tumor Progression and Cancer Therapy
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Science"
DOI: 10.1002/advs.202207366
Abstract: Gut microbiota‐derived metabolites are key hubs connecting the gut microbiome and cancer progression, primarily by remodeling the tumor microenvironment and regulating key signaling pathways in cancer cells and multiple immune cells. The use of microbial… read more here.
Keywords: microbial metabolites; gut microbiota; derived metabolites; cancer ... See more keywords
The influence of acute and chronic coronary syndrome on the gut microbiome and downstream microbiome-derived metabolites—Microbiome in acute myocardial infarction—MIAMI-Trial
Sign Up to like & getrecommendations! Published in 2025 at "Basic Research in Cardiology"
DOI: 10.1007/s00395-025-01134-9
Abstract: Cardiovascular diseases (CVD) are the leading cause of morbidity and mortality in the industrialized world. The gut microbiome influences CVD, through atherogenic metabolites like trimethylamine N-oxide (TMAO) or protective effects through short-chain fatty acids (SCFA)… read more here.
Keywords: microbiome; coronary syndrome; gut microbiome; derived metabolites ... See more keywords
Microbiota-derived metabolites as diagnostic markers for respiratory fungal infections.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical and biomedical analysis"
DOI: 10.1016/j.jpba.2020.113473
Abstract: An emerging body of evidence has highlighted the significant role of the pulmonary microbiota during respiratory infections. The individual microbiome is nowadays recognized to supervise the outcome of the host-pathogen interaction by orchestrating mechanisms of… read more here.
Keywords: respiratory fungal; metabolites diagnostic; diagnostic markers; microbiota derived ... See more keywords
The inhibitory effect of flavonoids and their gut-derived metabolites on the replication of Chlamydia abortus in the AH-1 ovine trophoblast cell line.
Sign Up to like & getrecommendations! Published in 2019 at "Research in veterinary science"
DOI: 10.1016/j.rvsc.2019.09.006
Abstract: The obligate intracellular bacterium Chlamydia abortus causes abortion and constitutes a worldwide threat for livestock. Plant-derived flavonoids have antimicrobial effects against veterinary and human pathogens and may be of help in the fight against C.… read more here.
Keywords: chlamydia abortus; derived metabolites; abortus; ovine trophoblast ... See more keywords
Gut Microbiota-Derived Metabolites and Cardiovascular Disease: Focus on Trimethylamine-N-oxide.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c08378
Abstract: Cardiovascular disease remains the leading cause of global morbidity and mortality, with growing evidence highlighting the role of gut microbiota-derived metabolites in its pathogenesis. Among these, trimethylamine-N-oxide (TMAO) has emerged as a key pro-atherogenic metabolite… read more here.
Keywords: gut microbiota; derived metabolites; gut; cardiovascular disease ... See more keywords
Neuroprotective Effects of Bioavailable Polyphenol-Derived Metabolites against Oxidative Stress-Induced Cytotoxicity in Human Neuroblastoma SH-SY5Y Cells.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.6b04538
Abstract: Oxidative stress is involved in cell death in neurodegenerative diseases. Dietary polyphenols can exert health benefits, but their direct effects on neuronal cells are debatable because most phenolics are metabolized and do not reach the… read more here.
Keywords: human neuroblastoma; stress; derived metabolites; sy5y cells ... See more keywords
Implications of Gut Microbiota-Derived Metabolites in Neurological Disorders.
Sign Up to like & getrecommendations! Published in 2025 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.5c00414
Abstract: Neurological disorders (NDs) represent a significant global health challenges, with neurodegeneration being a common pathological feature. Recent investigations indicate the involvement of gut microbiota-derived metabolites in these disorders, such as neuroinflammation, oxidative stress, and cognitive… read more here.
Keywords: brain; gut microbiota; derived metabolites; neurological disorders ... See more keywords
Gut Microbiota and Their Metabolites in Stroke: A Double-Edged Sword
Sign Up to like & getrecommendations! Published in 2022 at "Stroke"
DOI: 10.1161/strokeaha.121.036800
Abstract: Besides damaging the brain, stroke causes systemic changes, including to the gastrointestinal system. A growing body of evidence supports the role of the gut and its microbiota in stroke, stroke prognosis, and recovery. The gut… read more here.
Keywords: gut; gut microbiota; derived metabolites; stroke ... See more keywords
Loss of Microbiota-Derived Metabolites Is Associated with Mucosal-Barrier-Injury Bloodstream Infection in Patients Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Sign Up to like & getrecommendations! Published in 2024 at "Blood"
DOI: 10.1182/blood-2024-193273
Abstract: Background Conditioning for allogeneic hematologic stem cell transplantation (allo-SCT) is associated with mucosal barrier injury (MBI) and neutropenia. This results in a high risk of infection and, consequently, in higher mortality, with more than 40%… read more here.
Keywords: bloodstream; derived metabolites; microbiota derived; allo sct ... See more keywords
In utero human intestine contains maternally derived bacterial metabolites
Sign Up to like & getrecommendations! Published in 2025 at "Microbiome"
DOI: 10.1186/s40168-025-02110-0
Abstract: Understanding when host-microbiome interactions are first established is crucial for comprehending normal development and identifying disease prevention strategies. Furthermore, bacterially derived metabolites play critical roles in shaping the intestinal immune system. Recent studies have demonstrated… read more here.
Keywords: intestine; utero human; maternally derived; derived metabolites ... See more keywords
Microbiota-derived metabolites in colorectal cancer patients in preoperative period.
Sign Up to like & getrecommendations! Published in 2023 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202302_31384
Abstract: OBJECTIVE Short-chain fatty acids (SCFAs) are microbial derived metabolites, which have multiple beneficial properties. The amount of SCFAs depends on several factors, such as age, diet (mainly intake of dietary fiber), and overall health condition.… read more here.
Keywords: period; proportion scfas; colorectal cancer; crc patients ... See more keywords