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Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202102332
Abstract: Extracellular vesicle‐derived microRNA (EV‐miRNA) represent a promising cancer biomarker for disease diagnosis and monitoring. However, existing techniques to detect EV‐miRNA rely on complex, bias‐prone strategies, and preprocessing steps, making absolute quantification highly challenging. This work…
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Keywords:
extracellular vesicle;
derived microrna;
detection;
vesicle derived ... See more keywords
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Published in 2020 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c00680
Abstract: Current CRISPR-Cas-based nucleic acid sensing methods relying on the pre-assembled Cas-crRNA complexes are gen-erally limited to the detection of protospacer-adjacent motif (PAM)-containing sequences, and nonspecific back-grounds are inevitable. Herein, we propose a new CRISPR-derived microRNA…
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Keywords:
crispr;
rct;
cas12a;
crispr derived ... See more keywords