Macrophage‐derived MMP‐9 enhances the progression of atherosclerotic lesions and vascular calcification in transgenic rabbits
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.15087
Abstract: Matrix metalloproteinase‐9 (MMP‐9), or gelatinase B, has been hypothesized to be involved in the progression of atherosclerosis. In the arterial wall, accumulated macrophages secrete considerable amounts of MMP‐9 but its pathophysiological functions in atherosclerosis have… read more here.
Keywords: derived mmp; calcification; macrophage; macrophage derived ... See more keywords
A loss of host-derived MMP-7 promotes myeloma growth and osteolytic bone disease in vivo
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Cancer"
DOI: 10.1186/s12943-017-0616-9
Abstract: Matrix metalloproteinases (MMPs) play a critical role in cancer pathogenesis, including tumor growth and osteolysis within the bone marrow microenvironment. However, the anti-tumor effects of MMPs are poorly understood, yet have significant implications for the… read more here.
Keywords: derived mmp; host derived; bone; host ... See more keywords