Variable susceptibility of intestinal organoid–derived monolayers to SARS-CoV-2 infection
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DOI: 10.1101/2021.07.16.452680
Abstract: Gastrointestinal effects associated with COVID-19 are highly variable for reasons that are not understood. In this study, we used intestinal organoid-derived cultures differentiated from primary human specimens as a model to examine inter-individual variability. Infection… read more here.
Keywords: derived monolayers; intestinal organoid; infection; organoid derived ... See more keywords
Human duodenal organoid‐derived monolayers serve as a suitable barrier model for duodenal tissue
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DOI: 10.1111/nyas.14804
Abstract: Usually, duodenal barriers are investigated using intestinal cell lines like Caco‐2, which in contrast to native tissue are limited in cell‐type representation. Organoids can consist of all intestinal cell types and are supposed to better… read more here.
Keywords: cell; derived monolayers; barrier; duodenal tissue ... See more keywords
Establishment of bovine 3D enteroid-derived 2D monolayers
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DOI: 10.1186/s13567-022-01033-0
Abstract: Three-dimensional (3D) intestinal enteroids are powerful in vitro models for studying intestinal biology. However, due to their closed structure direct access to the apical surface is impeded, limiting high-throughput applications of exogenous compounds and pathogens.… read more here.
Keywords: establishment bovine; derived monolayers; cell; enteroid derived ... See more keywords