Structural and Dynamical Basis of G Protein Inhibition by YM-254890 and FR900359: An Inhibitor in Action
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DOI: 10.1021/acs.jcim.9b00433
Abstract: Specific inhibition of G proteins holds a great pharmacological promise to, e.g. target oncogenic Gq/11 proteins and can be achieved by the two natural products FR900359 (FR) and YM-254890 (YM). Unfortunately, recent rational-design-based approaches to… read more here.
Keywords: protein; inhibition; nmr structure; derived nmr ... See more keywords