Cinchona-Alkaloid-Derived NNP Ligand for Iridium-Catalyzed Asymmetric Hydrogenation of Ketones.
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DOI: 10.1021/acs.orglett.1c04101
Abstract: Most ligands applied for asymmetric hydrogenation are synthesized via multistep reactions with expensive chemical reagents. Herein, a series of novel and easily accessed cinchona-alkaloid-based NNP ligands have been developed in two steps. By combining [Ir(COD)Cl]2,… read more here.
Keywords: cinchona alkaloid; derived nnp; alkaloid derived; nnp ligand ... See more keywords