Pain relief in a neuropathy patient by lacosamide: Proof of principle of clinical translation from patient-specific iPS cell-derived nociceptors
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.11.042
Abstract: Background Small fiber neuropathy (SFN) is a severe and disabling chronic pain syndrome with no causal and limited symptomatic treatment options. Mechanistically based individual treatment is not available. We report an in-vitro predicted individualized treatment… read more here.
Keywords: patient specific; derived nociceptors; treatment; lacosamide ... See more keywords
Molecular identity, anatomy, gene expression and function of neural crest vs. placode-derived nociceptors in the lower airways
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DOI: 10.1016/j.neulet.2020.135505
Abstract: The lower airways (larynx to alveoli) are protected by a complex array of neural networks that regulate respiration and airway function. Harmful stimuli trigger defensive responses such as apnea, cough and bronchospasm by activating a… read more here.
Keywords: lower airways; derived nociceptors; anatomy; gene expression ... See more keywords