Rapid surface display of mRNA antigens by bacteria-derived outer membrane vesicles for a personalized tumor vaccine.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced materials"
DOI: 10.1002/adma.202109984
Abstract: Therapeutic mRNA vaccination is an attractive approach to trigger antitumor immunity. However, the mRNA delivery technology for customized tumor vaccine is still limited. Herein, we employed bacteria-derived outer membrane vesicles (OMVs) as an mRNA delivery… read more here.
Keywords: tumor; bacteria derived; tumor vaccine; derived outer ... See more keywords
Helicobacter pylori‐derived outer membrane vesicles contribute to Alzheimer's disease pathogenesis via C3‐C3aR signalling
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12306
Abstract: Abstract The gut microbiota represents a diverse and dynamic population of microorganisms that can influence the health of the host. Increasing evidence supports the role of the gut microbiota as a key player in the… read more here.
Keywords: derived outer; outer membrane; alzheimer disease; pathology ... See more keywords
ASCs activate cGAS-type I IFNs-IL-7 axis via Pseudomonas aeruginosa-derived outer membrane vesicles to resolve pneumonia.
Sign Up to like & getrecommendations! Published in 2023 at "Stem cells"
DOI: 10.1093/stmcls/sxad016
Abstract: Mesenchymal stem cells (MSCs) therapy could efficiently attenuate LPS-induced acute lung injury and Pseudomonas aeruginosa (PA)-induced acute pneumonia. However, the underlying molecular mechanisms are still elusive. Here, we report that PA-derived outer membrane vesicles (OMVs)… read more here.
Keywords: derived outer; pneumonia; pseudomonas aeruginosa; ascs ... See more keywords