Human induced pluripotent stem cell-derived platelets loaded with lapatinib effectively target HER2+ breast cancer metastasis to the brain
Sign Up to like & getrecommendations! Published in 2021 at "Scientific Reports"
DOI: 10.1038/s41598-021-96351-2
Abstract: Prognosis of patients with HER2+ breast-to-brain-metastasis (BBM) is dismal even after current standard-of-care treatments, including surgical resection, whole-brain radiation, and systemic chemotherapy. Radiation and systemic chemotherapies can also induce cytotoxicity, leading to significant side effects. Studies… read more here.
Keywords: her2 breast; hipsc platelets; human induced; induced pluripotent ... See more keywords
Whole blood–derived platelets: keeping our platelet inventory whole
Sign Up to like & getrecommendations! Published in 2018 at "Transfusion"
DOI: 10.1111/trf.14225
Abstract: Whole blood–derived platelet (WBDP) distribution has declined dramatically in the United States from 32.3% in 2001 to only 7.6% in 2013. This national trend is not reflected in the greater Seattle area where WBDPs still… read more here.
Keywords: plt; blood; blood derived; derived platelets ... See more keywords