Pathophysiologic Characterization of a Novel Rabbit Model of Biliary Tract Infection-Derived Sepsis
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DOI: 10.1038/s41598-019-48462-0
Abstract: Biliary tract infection (BTI)-derived sepsis remains a serious problem with significant morbidity and mortality in the modern era of critical care management. Current animal models of BTI have relied mostly on injecting purified bacteria or… read more here.
Keywords: biliary tract; sepsis; derived sepsis; model ... See more keywords
Thrombin contributes to protective immunity in pneumonia‐derived sepsis via fibrin polymerization and platelet–neutrophil interactions
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Thrombosis and Haemostasis"
DOI: 10.1111/jth.13625
Abstract: Essentials Immunity and coagulation are linked during sepsis but the role of thrombin is not fully elucidated. We investigated the effect of thrombin inhibition on murine Klebsiella pneumosepsis outcome. Thrombin is crucial for survival and… read more here.
Keywords: immunity; via fibrin; pneumonia derived; derived sepsis ... See more keywords
Streptococcus pneumoniae Elaborates Persistent and Prolonged Competent State during Pneumonia-Derived Sepsis
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DOI: 10.1128/iai.00919-19
Abstract: The competence regulon of pneumococcus regulates both genetic transformation and virulence. However, competence induction during host infection has not been examined. By using the serotype 2 strain D39, we transcriptionally fused the firefly luciferase (luc)… read more here.
Keywords: pneumonia derived; competent state; competence; pneumonia ... See more keywords