A validated lineage-derived somatic truth data set enables benchmarking in cancer genome analysis
Sign Up to like & getrecommendations! Published in 2020 at "Communications Biology"
DOI: 10.1038/s42003-020-01460-9
Abstract: Existing cancer benchmark data sets for human sequencing data use germline variants, synthetic methods, or expensive validations, none of which are satisfactory for providing a large collection of true somatic variation across a whole genome.… read more here.
Keywords: derived somatic; lineage; lineage derived; somatic truth ... See more keywords
Suppression of endogenous retroviral enhancers in mouse embryos derived from somatic cell nuclear transfer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2022.1032760
Abstract: Endogenous retroviruses (ERVs) in the mammalian genome play diverse roles in embryonic development. These developmentally related ERVs are generally repressed in somatic cells and therefore are likely repressed in embryos derived from somatic cell nuclear… read more here.
Keywords: rltr45 int; int; derived somatic; scnt derived ... See more keywords