An Update on Adipose-Derived Stem Cells for Regenerative Medicine: Where Challenge Meets Opportunity.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202207334
Abstract: Over the last decade, adipose-derived stem cells (ADSCs) have attracted increasing attention in the field of regenerative medicine. ADSCs appear to be the most advantageous cell type for regenerative therapies owing to their easy accessibility,… read more here.
Keywords: derived stem; regenerative medicine; adipose derived; stem cells ... See more keywords
BMP‐2/TGF‐β1 gene insertion into ligament‐derived stem cells sheet promotes tendon–bone healing in a mouse
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology Journal"
DOI: 10.1002/biot.202200470
Abstract: Bone morphogenetic protein‐2 (BMP‐2) and transforming growth factor‐β1 (TGF‐β1) reportedly induce the osteogenic and tenogenic differentiation of anterior cruciate ligament (ACL)‐derived stem cells (LDSCs), respectively. However, few studies have investigated the effect of BMP‐2/TGF‐β1 on… read more here.
Keywords: bmp tgf; derived stem; gene insertion; bone ... See more keywords
Safety, feasibility and effectiveness of first in‐human administration of muscle‐derived stem/progenitor cells modified with connexin‐43 gene for treatment of advanced chronic heart failure
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.700
Abstract: To assess the safety and efficacy of transendocardial delivery of muscle‐derived stem/progenitor cells with connexin‐43 overexpression (Cx‐43‐MDS/PC) in advanced heart failure (HF). read more here.
Keywords: heart; muscle derived; heart failure; derived stem ... See more keywords
Adipose tissue‐derived stem cells inhibit hypertrophic scar (HS) fibrosis via p38/MAPK pathway
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27689
Abstract: The current study was designed to investigate the effects and underlying mechanisms of adipose tissue‐derived stem cells (ADSCs) on hypertrophic scar (HS) fibrosis. read more here.
Keywords: hypertrophic scar; derived stem; scar fibrosis; adipose tissue ... See more keywords
Bone marrow macrophage M2 polarization and adipose‐derived stem cells osteogenic differentiation synergistically promote rehabilitation of bone damage
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29297
Abstract: By differentiating into and the balance being regulated between M1 (pro‐inflammatory) and M2 (anti‐inflammatory) heterogeneous populations, macrophages play critical roles during the host immune response in various physiological contexts in both health and diseases. Besides… read more here.
Keywords: stem cells; derived stem; bone; differentiation ... See more keywords
Inducing differentiation of human urine‐derived stem cells into hepatocyte‐like cells by coculturing with human hepatocyte L02 cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.29301
Abstract: To investigate the possibility of inducing differentiation of human urine‐derived stem cells (hUSCs) into hepatocyte‐like cells by coculturing with human hepatocyte L02 cells in vitro. read more here.
Keywords: human urine; inducing differentiation; differentiation human; derived stem ... See more keywords
HIF1A/miR‐20a‐5p/TGFβ1 axis modulates adipose‐derived stem cells in a paracrine manner to affect the angiogenesis of human dermal microvascular endothelial cells
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29111
Abstract: Angiogenic cytokines secreted by the adipose‐derived stem cells (ADSCs) might promote the angiogenesis of endothelial cells. In the present study, we hypothesize that miR‐20a targets TGFB1 to modulate the transforming growth factor β1 (TGFβ1) secretion… read more here.
Keywords: stem cells; mir 20a; angiogenesis; derived stem ... See more keywords
mTOR signaling plays a critical role in the defects observed in muscle‐derived stem/progenitor cells isolated from a murine model of accelerated aging
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Research"
DOI: 10.1002/jor.23409
Abstract: Mice expressing reduced levels of ERCC1‐XPF (Ercc1−/Δ mice) demonstrate premature onset of age‐related changes due to decreased repair of DNA damage. Muscle‐derived stem/progenitor cells (MDSPCs) isolated from Ercc1−/Δ mice have an impaired capacity for cell… read more here.
Keywords: muscle derived; mtor signaling; derived stem; stem progenitor ... See more keywords
Mitochondrial transfer from aged adipose‐derived stem cells does not improve the quality of aged oocytes in C57BL/6 mice
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23129
Abstract: Female fertility declines dramatically over the age of 35 due to age‐related decreases in oocyte quality and quantity. Although mitochondrial transfer promises to be a technology that can improve the quality of such age‐impaired oocytes,… read more here.
Keywords: quality; mitochondrial transfer; derived stem; stem cells ... See more keywords
Molecular and immunohistochemical analysis of the urethra of female rats after induced trauma and intravenous therapy with muscle derived stem cells
Sign Up to like & getrecommendations! Published in 2018 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.23567
Abstract: To identify the urethral migration of muscle derived stem cells (MDSCs) after intravenous (IV) injection in rats that underwent vaginal distension (VD) and to analyze the effects of MDSC in the urethra of rats after… read more here.
Keywords: muscle; muscle derived; molecular immunohistochemical; derived stem ... See more keywords
In Vitro 3D Mechanical Stimulation to Tendon-Derived Stem Cells by Bioreactor.
Sign Up to like & getrecommendations! Published in 2021 at "Methods in molecular biology"
DOI: 10.1007/7651_2021_432
Abstract: Bioreactors can offer an advanced platform to provide conditions that mimic the native microenvironment, which can also provide stretching environment for mechanobiology research. Tendon-derived stem cells (TDSCs) are a type of mechanosensitive and multipotent cells,… read more here.
Keywords: stimulation; derived stem; mechanical stimulation; tendon derived ... See more keywords