Investigate the stemness of adult adipose‐derived stromal cells based on single‐cell RNA‐sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11898
Abstract: The cellular heterogeneity and genetic features of stemness of adipose‐derived stromal cells (ADSCs) remain unclear. Using single‐cell RNA sequencing (scRNA‐seq), we investigated the genomic features of the stemness gene in ADSCs with genetic variability. We… read more here.
Keywords: cell; derived stromal; stemness; adipose derived ... See more keywords
Comparative characterization of CD271+ and CD271− subpopulations of CD34+ human adipose‐derived stromal cells
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26496
Abstract: Adipose‐derived stromal/stem cells (ASCs) are promising candidates for cell‐based therapies. However, the lack of markers able to unequivocally identify these cells, the differential expression of cell surface molecules among stromal progenitors from different tissues and… read more here.
Keywords: human adipose; derived stromal; cd271; expression ... See more keywords
Enhanced protection against lipopolysaccharide‐induced acute lung injury by autologous transplantation of adipose‐derived stromal cells combined with low tidal volume ventilation in rats
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29936
Abstract: Adipose‐derived stromal cells (ADSCs) showed excellent capacity in regeneration and tissue protection. Low tidal volume ventilation (LVT) strategy demonstrates a therapeutic benefit on the treatment of acute lung injury/acute respiratory distress syndrome (ALI/ARDS). This study,… read more here.
Keywords: protection; derived stromal; adscs; treatment ... See more keywords
Cryopreserved Off‐the‐Shelf Allogeneic Adipose‐Derived Stromal Cells for Therapy in Patients with Ischemic Heart Disease and Heart Failure—A Safety Study
Sign Up to like & getrecommendations! Published in 2017 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.17-0040
Abstract: The present first‐in‐human clinical trial evaluated the safety and feasibility of a newly developed and cryopreserved Cardiology Stem Cell Centre adipose‐derived stromal cell (CSCC_ASC) product from healthy donors for intramyocardial injection in ten patients with… read more here.
Keywords: heart; derived stromal; heart disease; patients ischemic ... See more keywords
Cultivation of Adipose-Derived Stromal Cells on Intact Amniotic Membrane-Based Scaffold for Skin Tissue Engineering.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/7651_2018_173
Abstract: Application of cell-based skin substitutes has recently evolved as a novel treatment for hard-to-heal wounds. Here, we focus on the development of a novel skin substitute by seeding human adipose-derived stromal cells (ASCs) on acellular… read more here.
Keywords: amniotic membrane; derived stromal; stromal cells; cultivation adipose ... See more keywords
The safety and efficacy of autologous adipose-derived stromal vascular fraction for nonscarring alopecia: A systematic review
Sign Up to like & getrecommendations! Published in 2021 at "Archives of Dermatological Research"
DOI: 10.1007/s00403-021-02238-7
Abstract: Nonscarring alopecia, including androgenetic alopecia and alopecia areata, are common and can negatively impact quality of life. Recent clinical studies have investigated autologous, adipose-derived stromal vascular fraction (SVF) as a potentially beneficial treatment option. To… read more here.
Keywords: derived stromal; autologous adipose; treatment; hair ... See more keywords
CD40L-expressing CD4+ T cells prime adipose-derived stromal cells to produce inflammatory chemokines.
Sign Up to like & getrecommendations! Published in 2022 at "Cytotherapy"
DOI: 10.1016/j.jcyt.2022.01.006
Abstract: The therapeutic potential of culture-adapted adipose-derived stromal cells (ASCs) is largely related to their production of immunosuppressive factors that are inducible in vitro by priming with inflammatory stimuli, in particular tumor necrosis factor-α (TNFα) and… read more here.
Keywords: cd40l expressing; cd4 cells; derived stromal; adipose derived ... See more keywords
NR4A3 induces endothelial dysfunction through up-regulation of endothelial 1 expression in adipose tissue-derived stromal cells.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118727
Abstract: Hypertension is one of the most prevalent diseases worldwide. Increased synthesis of the vasoconstrictor peptide endothelin 1 (encoded by EDN1) might be responsible for high blood pressure. The present study further confirmed the abnormal EDN1… read more here.
Keywords: derived stromal; stromal cells; expression; huvecs ... See more keywords
Exendin-4 modifies adipogenesis of human adipose-derived stromal cells isolated from omentum through multiple mechanisms
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Obesity"
DOI: 10.1038/s41366-018-0024-2
Abstract: Background:Abdominal obesity is considered a major factor in the development of metabolic disorders. Glucagon-like peptide-1 (GLP-1) has been reported to have positive effects on improving body metabolism and to reducing insulin resistance. However, it remains… read more here.
Keywords: human adipose; isolated omentum; derived stromal; stromal cells ... See more keywords
Obtaining spontaneously beating cardiomyocyte-like cells from adipose-derived stromal vascular fractions cultured on enzyme-crosslinked gelatin hydrogels
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep41781
Abstract: Heart failure often develops after acute myocardial infarction because the injured myocardial tissue fails to recover or regenerate. Stem cell transplantation using adult cell sources, such as adipose-derived stromal vascular fraction (SVF), draws extensive attention.… read more here.
Keywords: derived stromal; cms; enzyme crosslinked; adipose derived ... See more keywords
Dynamic microfactories co-encapsulating osteoblastic and adipose-derived stromal cells for the biofabrication of bone units.
Sign Up to like & getrecommendations! Published in 2019 at "Biofabrication"
DOI: 10.1088/1758-5090/ab3e16
Abstract: Cells with differentiation potential into mesodermal types are the focus of emerging bone tissue engineering (TE) strategies as an alternative autologous source. When the source of cells is extremely limited or not readily accessible, such… read more here.
Keywords: derived stromal; stromal cells; bone; dynamic environment ... See more keywords