Megakaryocyte/platelet-derived TGF-β1 inhibits megakaryopoiesis in bone marrow by regulating thrombopoietin production in liver
Sign Up to like & getrecommendations! Published in 2022 at "Blood Advances"
DOI: 10.1182/bloodadvances.2021005977
Abstract: Key Points Loss of Tgfb1 expression in MKs increases MK production in BM and TPO expression in the liver. Inhibition of TGF-β1 might increase MK generation in vivo and in vitro. read more here.
Keywords: tgf inhibits; megakaryocyte platelet; production; inhibits megakaryopoiesis ... See more keywords
Adipose-Derived Stem Cells Promote Bone Coupling in Bisphosphonate-Related Osteonecrosis of the Jaw by TGF-β1
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.639590
Abstract: This study aimed to investigate molecularly targeted therapy to revive bone remodeling and prevent BRONJ by local adipose-derived stem cells (ADSCs) transplantation. Clinical samples of BRONJ and healthy jawbones were used to examine the bone… read more here.
Keywords: adscs derived; derived tgf; bone; stem cells ... See more keywords
Platelet-derived TGF-β1 is related to portal vein thrombosis in cirrhosis by promoting hypercoagulability and endothelial dysfunction
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.938397
Abstract: Background Portal vein thrombosis (PVT) is a serious complication of cirrhosis accompanied by unclear pathogenesis. Transforming growth factor-beta (TGF-β) has been implicated in atherosclerosis and venous thrombosis whereas study regarding its part in PVT is… read more here.
Keywords: thrombosis; dysfunction; derived tgf; platelet derived ... See more keywords
Eosinophil-derived TGFβ1 controls the new bone formation in chronic rhinosinusitis with nasal polyps.
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DOI: 10.4193/rhin22.439
Abstract: BACKGROUND Chronic rhinosinusitis with nasal polyps (CRSwNP) is characterized by chronic eosinophilic inflammation and new bone formation (NBF). These processes may be associated with each other in the pathogenesis and influence the severity and prognosis… read more here.
Keywords: bone formation; tgf; bone; bone cells ... See more keywords
Dedifferentiated Schwann cell-derived TGF-β3 is essential for the neural system to promote wound healing
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DOI: 10.7150/thno.72317
Abstract: Rationale: Wound healing is among the most complicated physiological processes and requires the synchronization of various cell types with distinct roles to re-establish the condition of the original skin. Patients affected by peripheral neuropathies often… read more here.
Keywords: system; cell; wound healing; dedifferentiated schwann ... See more keywords