Patient‐derived in vitro skin models for investigation of small fiber pathology
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.50871
Abstract: To establish individually expandable primary fibroblast and keratinocyte cultures from 3‐mm skin punch biopsies for patient‐derived in vitro skin models to investigate of small fiber pathology. read more here.
Keywords: derived vitro; skin models; vitro skin; small fiber ... See more keywords
Patient-Derived In Vitro Models of Microglial Function and Synaptic Engulfment in Schizophrenia
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DOI: 10.1016/j.biopsych.2022.01.004
Abstract: Multiple lines of evidence implicate dysregulated microglia-mediated synaptic pruning in the pathophysiology of schizophrenia. In vitro human cellular studies represent a promising means of pursuing this hypothesis, complementing efforts with animal models and postmortem human data… read more here.
Keywords: vitro models; derived vitro; schizophrenia; models microglial ... See more keywords
Effect of vitrification on the expression of genes in porcine blastocysts derived from in vitro matured oocytes
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DOI: 10.1080/19396368.2022.2072788
Abstract: Abstract This study aimed to examine the effect of vitrification on the expression of genes that are crucial for porcine early embryo development; cathepsin B (CTSB), growth differentiation factor 9 (GDF9), caudal type homeobox 2… read more here.
Keywords: derived vitro; vitrification; effect vitrification; expression ... See more keywords
Animal Disease Models and Patient-iPS-Cell-Derived In Vitro Disease Models for Cardiovascular Biology—How Close to Disease?
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DOI: 10.3390/biology12030468
Abstract: Simple Summary Currently, rodents and pigs are the primary disease models used in cardiovascular research. Generally, larger animals that are more closely related to humans are better-suited disease models. However, they can have restricted or… read more here.
Keywords: derived vitro; vitro disease; disease; disease models ... See more keywords