High stroma‐derived WNT5A is an indicator for low‐risk prostate cancer
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DOI: 10.1002/2211-5463.13131
Abstract: Prostate cancer (PCa) is a major cause of cancer‐related death in men. Tumor‐derived protein derived from Wnt5A gene (WNT5A) plays an important role in primary and metastatic PCa. Surrounding stroma cells also produce WNT5A, which… read more here.
Keywords: risk; stroma derived; high risk; derived wnt5a ... See more keywords
Deletion of Wnt5a in osteoclasts results in bone loss through decreased bone formation
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DOI: 10.1111/nyas.14293
Abstract: Bone remodeling is achieved through the coupled activities of osteoclasts and osteoblasts that are controlled by many locally generated secreted factors, including WNT5A. While previous studies have demonstrated that osteoblast‐derived WNT5A promotes osteoclastogenesis, the function… read more here.
Keywords: decreased bone; bone formation; derived wnt5a; bone ... See more keywords