DERL3 suppresses colorectal cancer metastasis through negatively regulating MYCN level.
Sign Up to like & getrecommendations! Published in 2020 at "Minerva medica"
DOI: 10.23736/s0026-4806.20.06657-4
Abstract: BACKGROUND To illustrate the role of DERL3 in regulating the development of Colorectal cancer (CRC) and the underlying molecular mechanisms. METHODS Relative levels of DERL3 in CRC tissues and adjacent normal ones were detected by… read more here.
Keywords: metastasis; level; crc; derl3 ... See more keywords
Integrated profiling of endoplasmic reticulum stress-related DERL3 in the prognostic and immune features of lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.906420
Abstract: Background DERL3 has been implicated as an essential element in the degradation of misfolded lumenal glycoproteins induced by endoplasmic reticulum (ER) stress. However, the correlation of DERL3 expression with the malignant phenotype of lung adenocarcinoma… read more here.
Keywords: endoplasmic reticulum; lung adenocarcinoma; reticulum stress; derl3 ... See more keywords