Engineered Extracellular Vesicles Derived from Dermal Fibroblasts Attenuate Inflammation in a Murine Model of Acute Lung Injury.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced materials"
DOI: 10.1002/adma.202210579
Abstract: Acute respiratory distress syndrome (ARDS) represents a significant burden to the health care system, with approximately 200,000 cases diagnosed annually in the US. ARDS patients suffer from severe refractory hypoxemia, alveolar-capillary barrier dysfunction, impaired surfactant… read more here.
Keywords: dermal fibroblasts; inflammation; engineered extracellular; lung ... See more keywords
Skin aging: Dermal adipocytes metabolically reprogram dermal fibroblasts
Sign Up to like & getrecommendations! Published in 2021 at "BioEssays"
DOI: 10.1002/bies.202100207
Abstract: Emerging data connects the aging process in dermal fibroblasts with metabolic reprogramming, provided by enhanced fatty acid oxidation and reduced glycolysis. This switch may be caused by a significant expansion of the dermal white adipose… read more here.
Keywords: dermal fibroblasts; aging dermal; metabolically reprogram; skin aging ... See more keywords
Keratinocyte‐Releasable Factors Stimulate the Expression of Granulocyte Colony‐Stimulating Factor in Human Dermal Fibroblasts
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.25638
Abstract: Interaction between keratinocytes and fibroblasts plays a critical role in maintaining skin integrity under both normal and pathological conditions. We have previously demonstrated that keratinocyte‐releasable factors influence the expression of key extracellular matrix components, such… read more here.
Keywords: releasable factors; keratinocyte releasable; expression; factor ... See more keywords
Protective effects of Capsicum fruits and their constituents on damages in TNF-α-stimulated human dermal fibroblasts.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.12313
Abstract: BACKGROUND Antioxidant and anti-inflammatory effects of natural products on skin cells have been proved to be effective in improving skin damages. Capsicum species contain capsaicinoids which have antioxidant and anti-inflammatory properties, and various subspecies are… read more here.
Keywords: dermal fibroblasts; tnf stimulated; protective effects; human dermal ... See more keywords
An In Vitro Model of Cellular Quiescence in Primary Human Dermal Fibroblasts.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7371-2_2
Abstract: Cellular quiescence is a reversible mode of cell cycle exit that allows cells and organisms to withstand unfavorable stress conditions. The factors that underlie the entry, exit, and maintenance of the quiescent state are crucial… read more here.
Keywords: human dermal; vitro model; quiescence; model cellular ... See more keywords
MiR-210-5p regulates STAT3 activation by targeting STAT5A in the differentiation of dermal fibroblasts
Sign Up to like & getrecommendations! Published in 2021 at "3 Biotech"
DOI: 10.1007/s13205-021-02777-w
Abstract: Elucidating the molecular mechanism of the microRNAs in skin fibrosis is critical for identifying a novel therapeutic strategy for hypertrophic scar (HS). In this study, it was shown that miR-210-5p is induced by TGFβ, and… read more here.
Keywords: differentiation; tgf induced; mir 210; activation ... See more keywords
Identification of neutral and acidic glycosphingolipids in the human dermal fibroblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical biochemistry"
DOI: 10.1016/j.ab.2019.113348
Abstract: Skin fibroblasts are recognized as a valuable model of primary human cells able of mirroring the chronological and biological aging. Here, a lipidomic study of glycosphingolipids (GSL) occurring in the easily accessible human dermal fibroblasts… read more here.
Keywords: d18 d18; human dermal; identification neutral; neutral acidic ... See more keywords
Astragaloside exerts anti-photoaging effects in UVB-induced premature senescence of rat dermal fibroblasts through enhanced autophagy.
Sign Up to like & getrecommendations! Published in 2018 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2018.09.007
Abstract: BACKGROUND Astragalus membranaceus is a fundamental herb in Traditional Chinese Medicine and has attracted significant attention due to its anti-inflammatory, and longevity effects. However, its anti-photoaging property remains to be defined. Autophagy plays important roles… read more here.
Keywords: col1; rat dermal; anti photoaging; uvb induced ... See more keywords
CPEB1 or CPEB4 knockdown suppresses the TAK1 and Smad signalings in THP-1 macrophage-like cells and dermal fibroblasts.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108322
Abstract: Post-burn hypertrophic scar (HTS) is a form of excessive dermal fibrosis characterized by cutaneous scarring, which is common in patients following burn injury. Moreover, at least 50% of HTS are accompanied by inflammation. Cytoplasmic polyadenylation… read more here.
Keywords: tak1 smad; cpeb4 knockdown; smad signalings; cpeb1 cpeb4 ... See more keywords
Induction of dermal fibroblasts into dermal papilla cell-like cells in hydrogel microcapsules for enhanced hair follicle regeneration
Sign Up to like & getrecommendations! Published in 2020 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2020.100805
Abstract: Abstract Current approaches fail at obtaining adequate functional human dermal papilla cells (DPCs) to regenerate hair follicles (HFs). Here we induce human dermal fibroblasts (hDFs) into hDPC-like cells (hDF-DPCs) through alginate-poly-L-lysine-alginate (APA) microencapsulation. Our results… read more here.
Keywords: hydrogel microcapsules; hair follicle; like cells; induction dermal ... See more keywords
UVA-induced photoaging inhibits autophagic degradation by impairing lysosomal function in dermal fibroblasts.
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2019.08.103
Abstract: Autophagy has been associated with a variety of diseases especially aging. Human dermal fibroblasts (HDFs) can internalize and then degrade elastin, collagen and advanced glycation end products (AGEs) in lysosomes, which plays prominent roles in… read more here.
Keywords: degradation; uva induced; induced photoaging; photoaged fibroblasts ... See more keywords