Overexpression of miR-122 promotes apoptosis of dermal papilla cells by directly targeting IGF1R in androgenetic alopecia.
Sign Up to like & getrecommendations! Published in 2021 at "Cell biology international"
DOI: 10.1002/cbin.11723
Abstract: Androgenetic alopecia (AGA) is the most common pattern of hair loss resulting from the effects of androgen on hair follicle. MicroRNAs (miRs) serve imperative roles in the regulation of many biological processes of hair follicle.… read more here.
Keywords: papilla cells; dermal papilla; mir 122; androgenetic alopecia ... See more keywords
Expression dynamics of lymphoid enhancer‐binding factor 1 in terminal Schwann cells, dermal papilla, and interfollicular epidermis
Sign Up to like & getrecommendations! Published in 2022 at "Developmental Dynamics"
DOI: 10.1002/dvdy.562
Abstract: Transcription factor lymphoid enhancer‐binding factor 1 (LEF1) is a downstream mediator of the Wnt/β‐catenin signaling pathway. It is expressed in dermal papilla and surrounding cells in the hair follicle, promoting cell proliferation, and differentiation. read more here.
Keywords: binding factor; lymphoid enhancer; dermal papilla; factor ... See more keywords
Establishment of an in vitro organoid model of dermal papilla of human hair follicle
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.26853
Abstract: Human hair dermal papilla (DP) cells are specialized mesenchymal cells that play a pivotal role in hair regeneration and hair cycle activation. The current study aimed to first develop three‐dimensional (3D) DP spheroids (DPS) with… read more here.
Keywords: human hair; hair; vitro organoid; model ... See more keywords
Induction of hair follicle neogenesis with cultured mouse dermal papilla cells in de novo regenerated skin tissues
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Tissue Engineering and Regenerative Medicine"
DOI: 10.1002/term.2918
Abstract: De novo skin regeneration with human keratinocytes amplified in culture is a life‐saving procedure for patients with extensive skin loss and chronic wounds. It also provides a valuable platform for gene function and therapeutic assessments.… read more here.
Keywords: skin tissues; hair follicle; dermal papilla; papilla cells ... See more keywords
Preliminary studies of hair follicle regeneration by injections of epidermal stem cells and dermal papilla cells into nude mice
Sign Up to like & getrecommendations! Published in 2020 at "Cell and Tissue Banking"
DOI: 10.1007/s10561-020-09825-4
Abstract: The ultimate goal of organ regenerative therapy is to reproduce fully functional organs to replace which have been damaged as a result of diseases or injury. Although several studies claimed that using different types of… read more here.
Keywords: hair follicle; papilla cells; cells dermal; epidermal stem ... See more keywords
Induction of dermal fibroblasts into dermal papilla cell-like cells in hydrogel microcapsules for enhanced hair follicle regeneration
Sign Up to like & getrecommendations! Published in 2020 at "Applied Materials Today"
DOI: 10.1016/j.apmt.2020.100805
Abstract: Abstract Current approaches fail at obtaining adequate functional human dermal papilla cells (DPCs) to regenerate hair follicles (HFs). Here we induce human dermal fibroblasts (hDFs) into hDPC-like cells (hDF-DPCs) through alginate-poly-L-lysine-alginate (APA) microencapsulation. Our results… read more here.
Keywords: hydrogel microcapsules; hair follicle; like cells; induction dermal ... See more keywords
Combinatorial expression of cell cycle regulators is more suitable for immortalization than oncogenic methods in dermal papilla cells
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DOI: 10.1016/j.isci.2020.101929
Abstract: Summary The immortalized cell is an essential research tool that uses robust growth properties for the functional investigation of gene products. Immortalized mammalian cells have mainly been established using three methods: expression of simian vacuolating… read more here.
Keywords: papilla cells; combinatorial expression; method; expression ... See more keywords
Androgens modify Wnt agonists/antagonists expression balance in dermal papilla cells preventing hair follicle stem cell differentiation in androgenetic alopecia
Sign Up to like & getrecommendations! Published in 2017 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2016.10.018
Abstract: In androgenetic alopecia, androgens impair dermal papilla-induced hair follicle stem cell (HFSC) differentiation inhibiting Wnt signaling. Wnt agonists/antagonists balance was analyzed after dihydrotestosterone (DHT) stimulation in androgen-sensitive dermal papilla cells (DPC) cultured as spheroids or… read more here.
Keywords: hfsc differentiation; wnt agonists; differentiation; agonists antagonists ... See more keywords
Injectable platelet rich fibrin facilitates hair follicle regeneration by promoting human dermal papilla cell proliferation, migration, and trichogenic inductivity.
Sign Up to like & getrecommendations! Published in 2021 at "Experimental cell research"
DOI: 10.1016/j.yexcr.2021.112888
Abstract: Hair follicle regeneration has been successful in mice but failed in human being for years. Dermal papilla cells, a specialized mesenchymal stem cell derived from dermal papilla within hair follicles, is considered the key cells… read more here.
Keywords: follicle regeneration; hair follicle; regeneration; cell ... See more keywords
Mangifera Indica leaf extracts promote hair growth via activation of Wnt signaling pathway in human dermal papilla cells
Sign Up to like & getrecommendations! Published in 2022 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2022.2085790
Abstract: ABSTRACT The crosstalk between androgens and Wnt signaling pathways is critical in the hair growth cycle. Therefore, natural products that target these two pathways for the inhibition of hair loss are sought after. In this… read more here.
Keywords: growth; papilla cells; hair growth; dermal papilla ... See more keywords
Dermal papilla cell culture under hypoxia
Sign Up to like & getrecommendations! Published in 2019 at "British Journal of Dermatology"
DOI: 10.1111/bjd.18274
Abstract: Hair loss is most frequently associated with aging or hormonal imbalances, which result in follicular stem cells not being able to regenerate hair follicles (HFs). Many patients take medication or have hair transplantation to resolve… read more here.
Keywords: hair; hypoxia; culture; dermal papilla ... See more keywords