Review of data on the dermal penetration of mineral oils and waxes used in cosmetic applications.
Sign Up to like & getrecommendations! Published in 2017 at "Toxicology letters"
DOI: 10.1016/j.toxlet.2017.07.899
Abstract: Mineral oils and waxes used in cosmetic products, also referred to as "personal care products" outside the European Union, are mixtures of predominantly saturated hydrocarbons consisting of straight-chain, branched and ring structures with carbon chain… read more here.
Keywords: oils waxes; used cosmetic; waxes used; dermal penetration ... See more keywords
Lateral Dermal Penetration Is Dependent on the Lipophilicity of Active Ingredients
Sign Up to like & getrecommendations! Published in 2022 at "Skin Pharmacology and Physiology"
DOI: 10.1159/000522633
Abstract: Introduction: With its large surface area, skin facilitates a topical administration of active ingredients, and thus percutaneous delivery to a specific target site. Due to its high barrier function and different diffusion characteristics, skin governs… read more here.
Keywords: skin; penetration; dermal penetration; lipophilicity active ... See more keywords
Influence of Massage and Skin Hydration on Dermal Penetration Efficacy of Nile Red from Petroleum Jelly—An Unexpected Outcome
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13122190
Abstract: The study aimed at comparing the influence of direct and indirect skin hydration as well as massage on the dermal penetration efficacy of active compounds. Nile red was used as a lipophilic drug surrogate and… read more here.
Keywords: dermal penetration; penetration efficacy; skin hydration; penetration ... See more keywords
Assessing the Dermal Penetration Efficacy of Chemical Compounds with the Ex-Vivo Porcine Ear Model
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14030678
Abstract: (1) Background: The ex vivo porcine ear model is often used for the determination of the dermal penetration efficacy of chemical compounds. This study investigated the influence of the post-slaughter storage time of porcine ears… read more here.
Keywords: penetration; chemical compounds; penetration efficacy; efficacy chemical ... See more keywords
Particle-Assisted Dermal Penetration—A Simple Formulation Strategy to Foster the Dermal Penetration Efficacy
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14051039
Abstract: (1) Background: The study systematically investigated the influence of dispersed particles within a topical formulation on the dermal penetration efficacy of active compounds that are dissolved in the water phase of this formulation. The aim… read more here.
Keywords: formulation; penetration; penetration efficacy; particle assisted ... See more keywords
Dermal Penetration Studies of Potential Phenolic Compounds Ex Vivo and Their Antioxidant Activity In Vitro
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11151901
Abstract: Phenolic compounds with miscellaneous biological activities are an interesting component in dermatology and cosmetology practices. The aim of our study was to determine the phenolic compounds released from emulsion, emulgel, gel, ointment, and oleogel formulations… read more here.
Keywords: antioxidant activity; activity; dermal penetration; penetration studies ... See more keywords