Probing the competitive inhibitor efficacy of frog-skin alpha helical AMPs identified against ACE2 binding to SARS-CoV-2 S1 spike protein as therapeutic scaffold to prevent COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Molecular Modeling"
DOI: 10.1007/s00894-022-05117-8
Abstract: In COVID-19 infection, the SARS-CoV-2 spike protein S1 interacts to the ACE2 receptor of human host, instigating the viral infection. To examine the competitive inhibitor efficacy of broad spectrum alpha helical AMPs extracted from frog… read more here.
Keywords: cov spike; spike protein; sars cov; dermaseptin ... See more keywords
Effect of Dermaseptin S4 on C. albicans Growth and EAP1 and HWP1 Gene Expression
Sign Up to like & getrecommendations! Published in 2020 at "Probiotics and Antimicrobial Proteins"
DOI: 10.1007/s12602-020-09685-0
Abstract: Increasing resistance and changes in the spectrum of Candida infections have generated considerable interest in the development of new antifungal molecules. The use of antimicrobial peptides (AMPs) appears to be a promising approach. Frog skin… read more here.
Keywords: eap1 hwp1; dermaseptin; gene expression; albicans growth ... See more keywords