Checkpoint Blockade–Induced Dermatitis and Colitis Are Dominated by Tissue-Resident Memory T Cells and Th1/Tc1 Cytokines
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DOI: 10.1158/2326-6066.cir-22-0362
Abstract: Greater understanding of immune-related adverse events (irAE) could lead to new approaches in overcoming them. The authors show immunopathology of irAE dermatitis is dominated by Th1/Tc1 TRM cells, suggesting topical JAK inhibitors as corticosteroid-sparing agents… read more here.
Keywords: blockade induced; induced dermatitis; th1 tc1; dermatitis colitis ... See more keywords