Descending dopaminergic control of brainstem locomotor circuits
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DOI: 10.1016/j.cophys.2018.12.004
Abstract: The locomotor role of meso-diencephalic dopaminergic (DA) neurons is traditionally associated with their ascending pathways to the basal ganglia, which project to the Mesencephalic Locomotor Region (MLR), a brainstem region controlling locomotion. However, descending DA… read more here.
Keywords: brainstem; brainstem locomotor; locomotor; control brainstem ... See more keywords
Dopamine receptor D2, but not D1, mediates descending dopaminergic pathway–produced analgesic effect in a trigeminal neuropathic pain mouse model
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DOI: 10.1097/j.pain.0000000000001414
Abstract: Abstract Neuropathic pain represents a challenge to clinicians because it is resistant to commonly prescribed analgesics due to its largely unknown mechanisms. Here, we investigated a descending dopaminergic pathway–mediated modulation of trigeminal neuropathic pain. We… read more here.
Keywords: dopaminergic pathway; descending dopaminergic; neuropathic pain; spinal trigeminal ... See more keywords
Role of Descending Dopaminergic Pathways in Pain Modulation
Sign Up to like & getrecommendations! Published in 2019 at "Current Neuropharmacology"
DOI: 10.2174/1570159x17666190430102531
Abstract: Abstract: Pain, especially when chronic, is a common reason patients seek medical care and it affects the quality of life and well-being of the patients. Unfortunately, currently available therapies for chronic pain are often inadequate… read more here.
Keywords: role; pain; dopaminergic pathways; role descending ... See more keywords