Selective deficiencies in descending inhibitory modulation in neuropathic rats: implications for enhancing noradrenergic tone
Sign Up to like & getrecommendations! Published in 2018 at "Pain"
DOI: 10.1097/j.pain.0000000000001300
Abstract: Abstract Pontine noradrenergic neurones form part of a descending inhibitory system that influences spinal nociceptive processing. Weak or absent descending inhibition is a common feature of chronic pain patients. We examined the extent to which… read more here.
Keywords: spontaneous firing; control; inhibitory control; neuropathic rats ... See more keywords
Electroacupuncture Potentiates Cannabinoid Receptor-Mediated Descending Inhibitory Control in a Mouse Model of Knee Osteoarthritis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Molecular Neuroscience"
DOI: 10.3389/fnmol.2018.00112
Abstract: Knee osteoarthritis (KOA) is a highly prevalent, chronic joint disorder, which can lead to chronic pain. Although electroacupuncture (EA) is effective in relieving chronic pain in the clinic, the involved mechanisms remain unclear. Reduced diffuse… read more here.
Keywords: inhibitory control; receptor; descending inhibitory; chronic pain ... See more keywords