Descending pain modulation: influence and impact
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Physiology"
DOI: 10.1016/j.cophys.2019.06.004
Abstract: A myriad of complex processes marry to drive pain perception in health and chronicity. A final step in proceedings involves the activation of top-down modulatory pathways that can act directly to attenuate or enhance perceived… read more here.
Keywords: pain; modulation influence; modulation; influence impact ... See more keywords
Diffuse noxious inhibitory controls and conditioned pain modulation: a shared neurobiology within the descending pain inhibitory system?
Sign Up to like & getrecommendations! Published in 2022 at "Pain"
DOI: 10.1097/j.pain.0000000000002719
Abstract: Descending pain inhibition is a key component of physiological and pathological pain processing. Various neurotransmitter systems underlie different descending pain inhibitory pathways. Their anatomical and functional details have recently been revealed; thanks to new techniques… read more here.
Keywords: neurobiology; inhibitory; pain; descending pain ... See more keywords
Potency of descending pain modulatory system is linked with peripheral sensory dysfunction in fibromyalgia
Sign Up to like & getrecommendations! Published in 2019 at "Medicine"
DOI: 10.1097/md.0000000000013477
Abstract: Abstract Fibromyalgia (FM) is characterized by chronic widespread pain whose pathophysiological mechanism is related to central and peripheral nervous system dysfunction. Neuropathy of small nerve fibers has been implicated due to related pain descriptors, psychophysical… read more here.
Keywords: system; pain; dysfunction; task ... See more keywords
Understanding the pain profile in patients with haemophilia: Impaired descending pain inhibition as measured by conditioned pain modulation
Sign Up to like & getrecommendations! Published in 2020 at "Haemophilia"
DOI: 10.1111/hae.13939
Abstract: Haemophilic arthropathy is associated with pain that often becomes chronic, likely caused by peripheral and central mechanisms. In the field of haemophilia, to our knowledge, the role of the descending pain pathway, which can also… read more here.
Keywords: understanding pain; patients haemophilia; profile patients; pain profile ... See more keywords
Neuropeptide W, an endogenous NPBW1 and NPBW2 ligand, produced an analgesic effect via activation of the descending pain modulatory system during a rat formalin test
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Pain"
DOI: 10.1177/1744806921992187
Abstract: Neuropeptide W (NPW) messenger ribonucleic acid (mRNA) and NPBW1 and/or NPBW2 mRNA are expressed in the descending pain inhibitory system. In the present study, we examined whether NPW microinjected into the descending pain inhibitory system,… read more here.
Keywords: system; analgesic effect; effect; rat formalin ... See more keywords
The effect of occipital nerve field stimulation on the descending pain pathway in patients with fibromyalgia: a water PET and EEG imaging study
Sign Up to like & getrecommendations! Published in 2018 at "BMC Neurology"
DOI: 10.1186/s12883-018-1190-5
Abstract: BackgroundFibromyalgia is a chronic disorder characterized by widespread musculoskeletal pain accompanied by fatigue, sleep, memory, and mood problems. Recently, occipital nerve field stimulation (ONS) has been proposed as an effective potential treatment for fibromyalgia-related pain.… read more here.
Keywords: cortex; stimulation; pain pathway; study ... See more keywords