Differential interactions of resting, activated, and desensitized states of the α7 nicotinic acetylcholine receptor with lipidic modulators
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DOI: 10.1073/pnas.2208081119
Abstract: The α7 nicotinic acetylcholine receptor is a pentameric ligand-gated ion channel that modulates neuronal excitability, largely by allowing Ca2+ permeation. Agonist binding promotes transition from a resting state to an activated state, and then rapidly… read more here.
Keywords: differential interactions; state; desensitized states; nicotinic acetylcholine ... See more keywords